3'-Deoxy-3'-fluorouridine

Basic Information

View in Editor

CAS Number

57944-13-5

Molecular Formula

C9H11FN2O5

Molecular Weight

246.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

°Cat760mmHg

Density

1.63±0.1 g/cm3 (20 ºC 760 Torr),

Refractive Index

1.608

SMILES

View in Editor

C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)F)O

InChI

InChI=1S/C9H11FN2O5/c10-6-4(3-13)17-8(7(6)15)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1

InChIKey

FVBOTRDLABQYMI-XVFCMESISA-N

LogP

-1.8746999999999998

Topological Polar Surface Area

104.54999999999998 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

374

Synonyms & References

English

3'-deoxy-3'-fluorouridine
1-(3-Deoxy-3-fluoro-.beta.-D-ribofuranosyl)uracil
1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)uracil
1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
3'-FLUORO-3'-DESOXYURIDINE
CAINDEXNAME:URIDINE,3'-DEOXY-3'-FLUORO
1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
AC-32290
DTXSID80206649
3'-fluoro-3'-desoxyuridine
F12924
CHEMBL2311159
3'-Deoxy-3'-fluorouridine
Uridine, 3'-deoxy-3'-fluoro-
FVBOTRDLABQYMI-XVFCMESISA-N
SCHEMBL1739821
57944-13-5
3'-Fluoro-3'-deoxyuridine
MFCD02683987
1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
3'-deoxy-3'-fluoro-uridine
3 inverted exclamation mark -Deoxy-3 inverted exclamation mark -fluorouridine
AKOS027339995
3??-Deoxy-3??-fluorouridine
1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

MDL Number

MFCD02683987

FAQ

What regulatory guidelines apply to 3'-Deoxy-3'-fluorouridine (CAS: 57944-13-5)?

3'-Deoxy-3'-fluorouridine (CAS: 57944-13-5) must comply with GHS (Globally Harmonized System of Classification and Labelling of Chemicals) for hazardous communication. In the EU, it is subject to REACH regulations for chemical registration, evaluation, authorization, and restriction. For FDA and EPA purposes, it should adhere to relevant food and environmental safety standards, ensuring that it is handled under appropriate guidelines to prevent adverse effects on health and the environment.

Are there alternatives to 3'-Deoxy-3'-fluorouridine (CAS: 57944-13-5) in synthesis?

Yes, there are several alternatives to 3'-Deoxy-3'-fluorouridine (CAS: 57944-13-5) in synthesis. Common alternatives include 3'-Deoxy-3'-azidothymidine and 2'-Deoxy-2'-fluorouridine, which can serve similar roles in antiviral and anticancer therapies. Other reagents such as 5-fluorouracil and its derivatives are also used as effective alternatives.

What is the market or research trend for 3'-Deoxy-3'-fluorouridine (CAS: 57944-13-5)?

The market for 3'-Deoxy-3'-fluorouridine (CAS: 57944-13-5) is growing due to its potential as an antiviral and anticancer agent. Research trends are focusing on its applications in developing new antiviral drugs and cancer therapies. There is also an increasing interest in its synthesis and purification methods to improve its efficacy and reduce costs. The trend suggests a positive demand outlook, driven by the ongoing need for effective treatments in these areas.

How should waste containing 3'-Deoxy-3'-fluorouridine (CAS: 57944-13-5) be handled?

Waste containing 3'-Deoxy-3'-fluorouridine (CAS: 57944-13-5) should be collected in appropriate containers and stored in a secure location. Incineration is a common method for disposal, but ensure it is performed under controlled conditions to minimize environmental impact. Alternatively, professional waste disposal services can handle the waste, ensuring it is managed in compliance with local regulations. It is crucial to follow all safety precautions and adhere to environmental protection guidelines to prevent contamination and harm to the environment.