(2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one

Basic Information

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CAS Number

578-86-9

Molecular Formula

C15H12O4

Molecular Weight

256.26 g/mol

Basic Physical Properties

Physical State

Powder

Melting Point

206-208°C

Boiling Point

529.5℃ at 760mmHg

Flash Point

207℃

Solubility

873.5 mg/L @ 25 °C (est)

SMILES

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c1cc(ccc1[C@@H]2CC(=O)c3ccc(cc3O2)O)O

InChI

InChI=1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1

InChIKey

FURUXTVZLHCCNA-AWEZNQCLSA-N

LogP

2.8043000000000013

Topological Polar Surface Area

66.76 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

335

Safety Information

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Storage Conditions

2-8℃

Synonyms & References

English

(S)-7-Hydroxy-2-(4-hydroxyphenyl)chroman-4-one
4',7-Dihydroxyflavanone
(2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one
Liquiritigenin
(2S)-7-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
LIQUIRITIGENIN(AS)
LIQUIRITIGENIN(P)
glycyrrhizine R-19
4′,7-Dihydroxyflavanone
(2S)-liquiritigenin
5-DEOXYFLAVANONE
LIQUIRTIGENIN
7-hydroxy-2-(4-hydroxy-phenyl)-chroman-4-one
T194LKP9W6
Menerba
(2S)-7-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
(2S)-2-(4-hydroxyphenyl)-7-oxidanyl-2,3-dihydrochromen-4-one
(2S)-7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-ben
(-)-(2S)-7,4'-Dihydroxyflavanone,(-)-(S)-4',7-Dihydroxyflavanone,(-)-Liquiritigenin,4',7-Dihydroxyfl...

MDL Number

MFCD00287289

FAQ

What is (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 578-86-9)?

The compound (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 578-86-9) is a flavonoid derivative with the chemical formula C15H12O5. It exhibits antioxidant properties and is characterized by its hydroxyphenyl group and chromenone ring structure. Commonly used in research and pharmaceutical applications, it is a key intermediate in the synthesis of bioactive compounds.

What are the main uses of (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 578-86-9)?

The compound (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 578-86-9) is primarily used in pharmaceutical research for its potential antioxidant and anti-inflammatory activities. It serves as a precursor in the development of drugs targeting oxidative stress. Additionally, it is employed in chemical synthesis and as a model compound for studying flavonoid derivatives in biological systems.

Is (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 578-86-9) safe?

The compound (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 578-86-9) is generally considered safe when handled properly. However, it may cause mild irritation to skin and eyes. Safety data sheets recommend using appropriate personal protective equipment (PPE) and working in a well-ventilated area. Always follow established safety protocols for chemical handling to minimize risks.

How should (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 578-86-9) be stored?

To ensure stability, (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one (CAS: 578-86-9) should be stored in a cool, dry place at 2-8°C, away from light. Keep in airtight containers to prevent moisture absorption and degradation. Avoid exposure to air and heat, and store in a well-ventilated area to maintain chemical integrity and safety.