N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide | CAS No. 577969-56-3

N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide

Basic Information

CAS Number

577969-56-3

Molecular Formula

C25H33N5O7

Molecular Weight

515.57 g/mol

AD

Basic Physical Properties

Cc1cc(=O)oc2c1ccc(c2)NC(=O)[C@H](CCCCNC(=O)C)NC(=O)[C@H](C)NC(=O)CNC(=O)C

InChI

InChI=1S/C25H33N5O7/c1-14-11-23(34)37-21-12-18(8-9-19(14)21)29-25(36)20(7-5-6-10-26-16(3)31)30-24(35)15(2)28-22(33)13-27-17(4)32/h8-9,11-12,15,20H,5-7,10,13H2,1-4H3,(H,26,31)(H,27,32)(H,28,33)(H,29,36)(H,30,35)/t15-,20-/m0/s1

InChIKey

SUCZARDVMMDJRT-YWZLYKJASA-N

LogP

0.4719200000000022

Topological Polar Surface Area

175.70999999999998 Ų

Hydrogen Bond Donor/Acceptor

5 / 12

Complexity

919

Synonyms & References

English

  • L-Lysinamide, N-acetylglycyl-L-alanyl-N6-acetyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7- yl)-
  • acetyl-Gly-Ala-(N-acetyl-Lys)-AMC
  • Ac-GAK(Ac)-AMC
  • Ac-Gly-Ala-Lys(Ac)-AMC
  • L-Lysinamide,N-acetylglycyl-L-alanyl-N6-acetyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
  • 7-(N-alpha-acetyl-glycyl-L-alanyl-N-epsilon-acetyl-L-lysyl)amino-4-methylcoumarin
  • BDBM24619
  • SUCZARDVMMDJRT-YWZLYKJASA-N
  • N-acetylglycyl-L-alanyl-N6-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide
  • (2S)-6-acetamido-2-[(2S)-2-(2-acetamidoacetamido)propanamido]-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide

MDL Number

MFCD11975032

FAQ

What are the physical and chemical properties of N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide (CAS: 577969-56-3)?

N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide is a crystalline compound with a molecular weight of approximately 616.5 g/mol. It is slightly soluble in water and has good solubility in common organic solvents. The compound exhibits moderate reactivity, particularly towards nucleophiles, and is stable under neutral and slightly acidic conditions. It is insoluble in non-polar solvents. This compound is known for its high stability and low toxicity.

How is N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide (CAS: 577969-56-3) typically synthesized?

N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide is synthesized via multistep organic synthesis, involving coupling reactions, acetylations, and condensations. Commonly, this compound is prepared using protected amino acid derivatives and chromene intermediates. The synthesis typically involves the use of catalytic amounts of acid or base, with yields ranging from 50% to 70%. Selectivity is good under optimized conditions.

What industries use N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide (CAS: 577969-56-3)?

N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide is primarily used in the pharmaceutical industry for its potential in drug discovery and development. It also finds applications in the sensor technology and biotechnology sectors due to its unique chemical structure and reactivity. This compound may also be utilized in the polymer industry for specialized polymer synthesis and modification.

What precautions should be taken when handling N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide (CAS: 577969-56-3)?

When handling N-Acetylglycyl-L-alanyl-N~6~-acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be carried out in a well-ventilated area, preferably a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. In case of skin contact, wash the affected area with soap and water. For eye contact, rinse with plenty of water and seek medical attention if necessary. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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