4-(4-Piperidyl)-1-butanol

Basic Information

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CAS Number

57614-92-3

Molecular Formula

C9H19NO

Molecular Weight

157.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

57-60 ºC

Boiling Point

122 ºC (12 Torr)

Density

0.921±0.06 g/cm3 (20 ºC 760 Torr),

Flash Point

88.2±10.5 ºC,

SMILES

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C1CNCCC1CCCCO

InChI

InChI=1S/C9H19NO/c11-8-2-1-3-9-4-6-10-7-5-9/h9-11H,1-8H2

InChIKey

YRKCHKQZWFMCPB-UHFFFAOYSA-N

LogP

1.1486

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

89.6

Synonyms & References

English

4-Piperidinebutanol
4-(4-Piperidyl)-1-butanol
4-piperidin-4-ylbutan-1-ol
4-(4-HYDROXYBUTYL)PIPERIDINE
4-piperidin-4-yl-butan-1-ol
4-(Piperidin-4-yl)butan-1-ol
SCHEMBL2544949
MFCD02178381
DTXSID80382795
DS-17235
4-(piperidin-4-yl)butan-1-ol;4-(4-Piperidyl)-1-butanol
AKOS006334536
CS-D0191
DB-349526
SB42968
SY011920
EN300-6497680
A869634
57614-92-3

MDL Number

MFCD02178381

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-(4-Piperidyl)-1-butanol (CAS: 57614-92-3)?

4-(4-Piperidyl)-1-butanol (CAS: 57614-92-3) is a colorless liquid with a molecular weight of 172.26 g/mol. It has a piperidine-like odor and is slightly soluble in water. The compound is reactive towards acidic and basic conditions. It crystallizes in the form of white needles at -10°C.

How is 4-(4-Piperidyl)-1-butanol (CAS: 57614-92-3) typically synthesized?

4-(4-Piperidyl)-1-butanol is typically synthesized via the reaction of 1-bromobutane with 4-piperidone. The process involves heating the mixture under reflux in the presence of a base like sodium hydroxide, followed by acidification to isolate the product. The yield is around 75-85%, with high selectivity towards the desired product.

What industries use 4-(4-Piperidyl)-1-butanol (CAS: 57614-92-3)?

4-(4-Piperidyl)-1-butanol (CAS: 57614-92-3) is primarily used in the pharmaceutical industry as a precursor for various drug molecules. It is also utilized in polymer manufacturing, sensor technology, and semiconductor processing due to its functional properties.

What precautions should be taken when handling 4-(4-Piperidyl)-1-butanol (CAS: 57614-92-3)?

When handling 4-(4-Piperidyl)-1-butanol (CAS: 57614-92-3), it is essential to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of skin contact, wash immediately with soap and water. For spills, neutralize with an appropriate acid or base and clean up with absorbent materials. Refer to the safety data sheet (SDS) for detailed information on handling and disposal.