(11beta)-11,21-Dihydroxy-3,20-dioxopregn-4-en-17-yl valerate

Basic Information

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CAS Number

57524-89-7

Molecular Formula

C26H38O6

Molecular Weight

446.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

217-220 ºC

Boiling Point

595.1°Cat760mmHg

Density

1.21±0.1 g/cm3 (20 ºC 760 Torr),

Flash Point

195°C

Solubility

Insuluble (3.3E-3 g/L) (25 ºC),

Refractive Index

1.56

SMILES

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CCCCC(=O)OC1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)C(=O)CO

InChI

InChI=1S/C26H38O6/c1-4-5-6-22(31)32-26(21(30)15-27)12-10-19-18-8-7-16-13-17(28)9-11-24(16,2)23(18)20(29)14-25(19,26)3/h13,18-20,23,27,29H,4-12,14-15H2,1-3H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1

InChIKey

FZCHYNWYXKICIO-FZNHGJLXSA-N

LogP

3.5227000000000026

Topological Polar Surface Area

100.90000000000002 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

832

Synonyms & References

English

Tox21_110853_1
(1R,3aS,3bS,9aR,9bS,10S,11aS)-10-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl pentanoate
CHEBI:50865
Hydrocortisone valerate [USAN]
Hydrocortisone valerate [USAN:USP]
EINECS 260-786-8
[(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] pentanoate
hydrocortisone valerate cream
FZCHYNWYXKICIO-FZNHGJLXSA-N
CS-0013050
SCHEMBL80603
Hydrocortisone valerate, United States Pharmacopeia (USP) Reference Standard
HMS2235G11
BCP20579
AC-13156
MLS001076102
CAS-57524-89-7
UNII-68717P8FUZ
DTXCID7025633
HYDROCORTISONE VALERATE (USP-RS)
Opera_ID_1123
Hydrocortisone valerate (USP)
NS00021223
HYDROCORTISONE VALERATE [VANDF]
HYDROCORTISONE VALERATE [USP-RS]
11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-valerate
HY-B1265
NSC 759133
Hydrocortisone-17-valerate
HYDROCORTISONE VALERATE (USP MONOGRAPH)
Pregn-4-ene-3,20-dione, 11,21-dihydroxy-17-((1-oxopentyl)oxy)-, (11beta)-

MDL Number

MFCD00083365

FAQ

What regulatory guidelines apply to (11beta)-11,21-Dihydroxy-3,20-dioxopregn-4-en-17-yl valerate (CAS: 57524-89-7)?

This compound falls under the scope of GHS for classification as a chemical substance. Regulatory guidelines include REACH in the European Union, which mandates registration, evaluation, authorization, and restriction of chemicals. In the United States, FDA and EPA regulations may apply based on specific applications and intended uses. Users should consult relevant regulatory bodies for detailed compliance requirements.

Are there alternatives to (11beta)-11,21-Dihydroxy-3,20-dioxopregn-4-en-17-yl valerate in synthesis?

For synthesis, several alternatives can be considered, such as using (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-ene-17-one or other steroidal valerate derivatives. These alternatives can offer similar functionalities. It is advisable to evaluate each alternative based on reaction specificity, yield, and cost-efficiency.

What is the market or research trend for (11beta)-11,21-Dihydroxy-3,20-dioxopregn-4-en-17-yl valerate?

Research trends indicate increasing interest in this compound for its potential in biopharmaceutical applications, particularly in hormone therapy and reproductive health. Market trends show growing demand, driven by advancements in drug development and regulatory approvals. Emerging studies focus on its pharmacokinetics and clinical efficacy.

How should waste containing (11beta)-11,21-Dihydroxy-3,20-dioxopregn-4-en-17-yl valerate be handled?

Waste containing this compound should be collected in a sealed container and disposed of according to local waste management regulations. For hazardous waste, professional disposal services should be utilized. Environmental protection measures include proper containment to prevent leaks and ensure safe transport to the disposal site. Users should consult local environmental agencies for specific disposal guidelines.