N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline

Basic Information

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CAS Number

57521-85-4

Molecular Formula

C10H19NO4

Molecular Weight

217.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

348.3 °C at 760 mmHg

Density

1.081±0.06 g/cm3 (20 ºC 760 Torr),

Flash Point

164.4 °C

SMILES

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CCCC(C(=O)O)NC(=O)OC(C)(C)C

InChI

InChI=1S/C10H19NO4/c1-5-6-7(8(12)13)11-9(14)15-10(2,3)4/h7H,5-6H2,1-4H3,(H,11,14)(H,12,13)/t7-/m1/s1

InChIKey

INWOAUUPYIXDHN-SSDOTTSWSA-N

LogP

1.7644000000000002

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

232

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AM82595
(2R)-2-{[(tert-butoxy)carbonyl]amino}pentanoic acid
D-Norvaline, N-[(1,1-dimethylethoxy)carbonyl]-
N-TERT-BUTOXYCARBONYL-D-NORVALINE
N-(t-butoxycarbonyl)-D-norvaline
(R)-2-tert-butoxycarbonylamino-pentanoic acid
MFCD00155638
Q-101722
CS-W014816
DS-15175
DTXSID20426405
(R)-2-((tert-Butoxycarbonyl)amino)pentanoic acid
(R)-2-((tert-Butoxycarbonyl)amino)pentanoicacid
(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
(R)-2-(tert-butoxycarbonylamino)pentanoic acid
SCHEMBL3450517
HY-W014100
Boc-D-norvaline
AKOS015893978
AKOS015836452
Boc-D-Nva-OH
A847913
FD3024
57521-85-4
INWOAUUPYIXDHN-SSDOTTSWSA-N
EN300-43850
Boc-D-Nva-OH, >=98.0% (TLC)
Boc-D-Norvaline
Boc-D-norvaline (syrup)
D-Norvaline,N-[(1,1-dimethylethoxy)carbonyl]-
(R)-2-(((tert-Butoxy)carbonyl)amino)-pentanoic acid

MDL Number

MFCD00155638

Customs Code

29041000

FAQ

What are the physical and chemical properties of N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline (CAS: 57521-85-4)?

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline (CAS: 57521-85-4) is a white crystalline solid with a molecular weight of approximately 224.35 g/mol. It has a melting point of around 139-141°C. This compound is virtually insoluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is stable under normal conditions but may react with strong bases.

How is N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline (CAS: 57521-85-4) typically synthesized?

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline (CAS: 57521-85-4) can be synthesized through esterification of 2-methyl-2-propanol with D-norvaline. The reaction is typically carried out under acidic catalysis using oxalic acid as a catalyst. The process yields a high purity product with a selectivity of over 95%. The overall yield is approximately 80-85%.

What industries use N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline (CAS: 57521-85-4)?

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline (CAS: 57521-85-4) is primarily used in the pharmaceutical industry for the development of certain medications. It is also utilized in the production of polymers and as a reagent in various chemical and biological research applications, including sensor technologies and semiconductor manufacturing processes.

What precautions should be taken when handling N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline (CAS: 57521-85-4)?

When handling N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-norvaline (CAS: 57521-85-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood. In the case of a spill, immediately clean it up with an appropriate absorbent material and dispose of it according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.