3-(Methoxymethyl)phenol

Basic Information

View in Editor

CAS Number

57234-51-2

Molecular Formula

C8H10O2

Molecular Weight

138.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

SMILES

View in Editor

COCC1=CC(=CC=C1)O

InChI

InChI=1S/C8H10O2/c1-10-6-7-3-2-4-8(9)5-7/h2-5,9H,6H2,1H3

InChIKey

AAVSHQOVBKPECT-UHFFFAOYSA-N

LogP

1.5386

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

93.3

Synonyms & References

English

DTXSID00555722
57234-51-2
SCHEMBL3150055
AKOS010766056
CS-0208759
Z821093526
3-(methoxymethyl)phenol
F83032
EN300-75883
BS-32578
Phenol, 3-(methoxymethyl)-

MDL Number

MFCD14680990

FAQ

What are the physical and chemical properties of 3-(Methoxymethyl)phenol (CAS: 57234-51-2)?

3-(Methoxymethyl)phenol is a white crystalline solid with a molecular weight of approximately 164.18 g/mol. It has a low water solubility, with a solubility of about 0.4 g/L at 20°C. The compound is moderately reactive, showing亲电性与羟基和甲氧甲基的反应性。

How is 3-(Methoxymethyl)phenol (CAS: 57234-51-2) typically synthesized?

3-(Methoxymethyl)phenol is typically synthesized via the reaction of phenol with methanol in the presence of a base like sodium hydride. The reaction proceeds with good yield and selectivity, although careful handling of the base and the solvent is necessary to avoid side reactions and ensure purity.

What industries use 3-(Methoxymethyl)phenol (CAS: 57234-51-2)?

3-(Methoxymethyl)phenol is used in various industries, including pharmaceuticals for synthesis of certain drug intermediates, polymers for its stability and reactivity, and in the development of sensors and semiconductors due to its chemical properties.

What precautions should be taken when handling 3-(Methoxymethyl)phenol (CAS: 57234-51-2)?

When handling 3-(Methoxymethyl)phenol, ensure that appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat is worn. Work in a well-ventilated area or fume hood to minimize inhalation risks. Store the compound in a cool, dry place, away from direct sunlight. In case of a spill, immediately clean up using appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further guidance.