(4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid

Basic Information

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CAS Number

5718-83-2

Molecular Formula

C5H5NO3S2

Molecular Weight

191.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

145.0 to 149.0 deg-C

Boiling Point

375.4°C at 760 mmHg

Flash Point

180.8℃

Solubility

methanol: soluble25mg/mL, clear, yellow

Refractive Index

1.5480 (estimate)

SMILES

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C1C(=O)N(C(=S)S1)CC(=O)O

InChI

InChI=1S/C5H5NO3S2/c7-3-2-11-5(10)6(3)1-4(8)9/h1-2H2,(H,8,9)

InChIKey

JGRMXPSUZIYDRR-UHFFFAOYSA-N

LogP

-0.0687000000000002

Topological Polar Surface Area

57.61 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

228

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

N-CARBOXYMETHYLRHODANINE
2-(4-oxo-2-thioxothiazolidin-3-yl)acetic acid
SY017106
MFCD00005491
C5H5NO3S2
3-(Carboxymethyl)rhodanine
3-carboxymethylrhodanine
5718-83-2
NSC40450
NCGC00247004-01
CS-0071814
F0385-0052
2-(4-oxo-2-thioxothiazolidin-3-yl)aceticacid
3-Rhodanineacetic acid
NS00033659
3-Thiazolidineacetic acid, 4-oxo-2-thioxo-
N-(Carboxymethyl)rhodanine
CHEMBL224441
AKOS000267584
SR-01000404570-1
(4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid #
Rhodanine-3-acetic acid
NSC 40450
EINECS 227-220-1
DTXSID1063986
NSC-40450
4-Oxo-2-thioxo-3-thiazolidinylacetic acid, >=99%
MLS001074868
EN300-16929
HMS2865C14
SMR000054752

MDL Number

MFCD00005491

Customs Code

29341000

FAQ

What is (4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid (CAS: 5718-83-2)?

(4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid, with CAS number 5718-83-2, is a heterocyclic compound containing a thiazolidine ring with two sulfur atoms. It is a white crystalline solid with moderate solubility in polar solvents and exhibits acidic properties due to the carboxylic acid group. This compound is often used as a building block in pharmaceutical synthesis.

What are the main uses of (4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid (CAS: 5718-83-2)?

(4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid (CAS: 5718-83-2) is primarily utilized in pharmaceutical research for developing antidiabetic and antibiotic drugs. It serves as a key intermediate in the synthesis of various bioactive molecules and is also applied in chemical research for creating derivatives with specific therapeutic properties.

Is (4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid (CAS: 5718-83-2) safe?

Safety of (4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid (CAS: 5718-83-2) depends on handling conditions. It is classified as a chemical intermediate with potential irritant properties; thus, protective measures like gloves, goggles, and proper ventilation are recommended. Always follow safety data sheet (SDS) guidelines for safe use in laboratory or industrial settings.

How should (4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid (CAS: 5718-83-2) be stored?

(4-Oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid (CAS: 5718-83-2) should be stored in a cool, dry place, away from light and moisture. Keep in a sealed container to maintain stability, and ensure proper ventilation to prevent exposure. Avoid storage near incompatible materials to ensure chemical safety.