3-Chloro-6-isopropylpyridazine

Basic Information

View in Editor

CAS Number

570416-35-2

Molecular Formula

C7H9ClN2

Molecular Weight

156.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Boiling Point

263 ºC

Density

1.135

Flash Point

138 ºC

SMILES

View in Editor

CC(C)c1ccc(Cl)nn1

InChI

InChI=1S/C7H9ClN2/c1-5(2)6-3-4-7(8)10-9-6/h3-5H,1-2H3

InChIKey

UYKSBKJSQWGYTQ-UHFFFAOYSA-N

LogP

2.2534

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H320 Causes eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-Chloro-6-isopropylpyridazine
3-chloro-6-propan-2-ylpyridazine
Pyridazine, 3-chloro-6-(1-methylethyl)-
3-Chloro-6-(1-methylethyl)pyridazine
3-chloro-6-(propan-2-yl)pyridazine

MDL Number

MFCD12143153

FAQ

What are the physical and chemical properties of 3-Chloro-6-isopropylpyridazine (CAS: 570416-35-2)?

The physical properties of 3-Chloro-6-isopropylpyridazine include a crystalline form with a molecular weight of approximately 202.62 g/mol. Its solubility is low in water but soluble in organic solvents like ethanol and acetone. This compound is moderately reactive, particularly towards nucleophilic substitution reactions. It is not flammable but can decompose at high temperatures, releasing toxic gases.

How is 3-Chloro-6-isopropylpyridazine (CAS: 570416-35-2) typically synthesized?

3-Chloro-6-isopropylpyridazine is typically synthesized via a nucleophilic substitution reaction. The reaction usually involves the substitution of a chlorine atom on pyridine with an isopropyl group. Commonly, this is achieved using isopropyl iodide and a base like triethylamine. The yield and selectivity of the reaction can be enhanced by using catalytic amounts of palladium compounds as catalysts.

What industries use 3-Chloro-6-isopropylpyridazine (CAS: 570416-35-2)?

3-Chloro-6-isopropylpyridazine is used in various industries. In the pharmaceutical industry, it acts as a precursor for the synthesis of certain drugs. In the chemical industry, it is employed in polymer synthesis and as a component in the production of sensors and semiconductors. Its versatility in these applications makes it a valuable compound.

What precautions should be taken when handling 3-Chloro-6-isopropylpyridazine (CAS: 570416-35-2)?

When handling 3-Chloro-6-isopropylpyridazine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to toxic fumes. Spills should be cleaned up using appropriate absorbent materials and proper disposal methods. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.