(3beta)-Cholest-5-en-3-ol

Basic Information

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CAS Number

57-88-5

Molecular Formula

C27H46O

Molecular Weight

386.66 g/mol

EINECS

200-353-2

Chemical Classification

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

Powder

Melting Point

147-149 °C

Boiling Point

360 °C

Density

1.06

Flash Point

250 ºC

Solubility

H2O: 0.002 mg/mL

Refractive Index

1.5250 (estimate)

Vapor Pressure

VP: 0.171 mm Hg at 149 °C

Odor

Almost odorless

Specific Rotation

-36 º (c=2, dioxane)

SMILES

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CC(C)CCCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C

InChI

InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChIKey

HVYWMOMLDIMFJA-DPAQBDIFSA-N

LogP

7.388700000000009

pKa

15.03±0.70(Predicted)

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

591

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Storage Conditions

2-8℃

Toxicity

Present in all parts of the animal body; concentrated in spinal cord, brain, skin secretions, and gallstones. An unsaturated, unsaponifiable alcohol (m.p. 149℃). It is synthesized in the body from ethanoate units; its metabolism is regulated by a specific set of enzymes. It is the parent compound of many other steroids and its presence in high concentrations in the blood is suspected as being a contributory factor in cardiovascular disease.

RTECS

FZ8400000

Synonyms & References

English

6-Cholesten-3b-ol
5-Cholesten-3beta-ol
cholesterol from lanolin
cholesterol from hog liver
Cholesterol, NF
(3beta)-cholest-5-en-3-ol
(3.beta.)-Cholest-5-en-3-ol
(3β)-cholest-5-en-3-ol
3β-hydroxycholest-5-ene
5,6-Cholesten-3beta-ol
5:6-cholesten-3-beta-ol
5:6-Cholesten-3beta-ol
5-Cholesten-3B-ol
5-cholesten-3β-ol
Cholest-5-en-3beta-ol
3beta-hydroxycholest-5-ene
3beta-hydroxy-5-cholestene
Cholesterol (stabilized with alpha-Tocopherol)
Cholest-5-en-3-ol
Cholest-5-en-3β-ol
Cholesterol
CHOLESTEROL (AS)
Cholesterol solution
Cholesterol, Semi-synthetic
20-Dihydro Cortexolone
20-Dihydro-11-deoxycortisol
3β-Hydroxy-5-cholestene
cholesterin
cholest-5-en-3β-ol ; 110796
cholest-5-en-3β-ol; 110797
CHO-HP

MDL Number

MFCD00669916

EC Number

200-353-2

Customs Code

2906131000

FAQ

What is (3beta)-Cholest-5-en-3-ol (CAS: 57-88-5)?

(3beta)-Cholest-5-en-3-ol, also known as cholesterol, is a steroid alcohol with the chemical formula C27H46O. It is a white crystalline solid, insoluble in water but soluble in organic solvents. This compound serves as a fundamental building block for steroid hormones, bile acids, and vitamin D. Its structure features a hydroxyl group at position 3 and a double bond at position 5, playing a critical role in cell membrane integrity and lipid metabolism. CAS 57-88-5 identifies this essential biomolecule in scientific and industrial contexts.

What are the main uses of (3beta)-Cholest-5-en-3-ol (CAS: 57-88-5)?

(3beta)-Cholest-5-en-3-ol is widely used in pharmaceuticals as a precursor for synthesizing corticosteroids, sex hormones, and bile acids. In the food industry, it is naturally present in animal-derived products and used as an emulsifier. Industrial applications include its role in producing soaps and detergents. Researchers utilize it to study lipid metabolism, membrane structure, and cholesterol-related diseases. Its versatility makes it a key compound across medicinal, nutritional, and scientific domains.

Is (3beta)-Cholest-5-en-3-ol (CAS: 57-88-5) safe?

(3beta)-Cholest-5-en-3-ol is generally safe in controlled amounts but requires proper handling. It may cause mild irritation to skin or eyes upon contact. Safety measures include wearing gloves, goggles, and lab coats to minimize exposure. Avoid inhalation and ingestion, and ensure adequate ventilation. While low toxicity is reported, adherence to safety data sheets (SDS) and regulatory standards is essential for safe use in laboratories and industrial environments.

How should (3beta)-Cholest-5-en-3-ol (CAS: 57-88-5) be stored?

(3beta)-Cholest-5-en-3-ol should be stored in a cool, dry, and dark place to prevent degradation. Keep in airtight containers to avoid moisture and humidity exposure. Maintain storage temperatures below 25°C and protect from light to preserve stability. Ensure proper ventilation to reduce inhalation risks. Correct storage conditions are crucial for maintaining the compound’s quality and safety during handling and use.