Pregn-4-ene-3,20-dione | CAS No. 57-83-0

Q: What is Pregn-4-ene-3,20-dione (CAS: 57-83-0)?

Pregn-4-ene-3,20-dione (CAS: 57-83-0) is a steroid compound with the chemical formula C21H30O2. It serves as a key intermediate in steroid hormone biosynthesis, featuring a pregnane ring system and two ketone groups. This compound is typically a white crystalline solid with low solubility in water. Its structural simplicity makes it valuable for research and industrial applications, while its reactivity influences its role in biochemical pathways and synthetic chemistry.

Q: What are the main uses of Pregn-4-ene-3,20-dione (CAS: 57-83-0)?

Pregn-4-ene-3,20-dione (CAS: 57-83-0) is primarily used in pharmaceuticals as a precursor for corticosteroids and other steroid-derived drugs. In research, it aids in studying hormone metabolism and synthetic pathways. Industrially, it serves as a chemical intermediate for producing pharmaceuticals and cosmetics. Its applications also extend to veterinary medicine and as a reference standard in analytical chemistry, highlighting its versatility in various sectors.

Q: Is Pregn-4-ene-3,20-dione (CAS: 57-83-0) safe?

Pregn-4-ene-3,20-dione (CAS: 57-83-0) is generally safe when handled properly, but it requires caution due to potential irritant properties. Safety standards emphasize avoiding skin contact and inhalation, with protective measures like gloves and ventilation recommended. While not classified as highly toxic, long-term exposure or ingestion should be avoided. Always follow OSHA guidelines and proper lab safety protocols for safe handling and disposal.

Q: How should Pregn-4-ene-3,20-dione (CAS: 57-83-0) be stored?

Pregn-4-ene-3,20-dione (CAS: 57-83-0) should be stored in a cool, dry place (2-8°C), away from light and moisture. Use sealed, airtight containers to maintain stability and prevent degradation. Avoid exposure to air or reactive substances to ensure long-term preservation. Proper storage conditions are critical to maintaining its chemical integrity and safety, particularly in industrial and research settings.

Pregn-4-ene-3,20-dione

Basic Information

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CAS Number

57-83-0

Molecular Formula

C21H30O2

Molecular Weight

314.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

Powder

Melting Point

128-132 °C

Boiling Point

394.13°C (rough estimate)

Water Solubility

<0.1 g/100 mL at 19 ºC

Flash Point

2℃(35.6℉)(lit.)

Solubility

H2O: 25 mg/mL, may be clear to slightly hazy

Refractive Index

182 ° (C=2, Dioxane)

Specific Rotation

186 º (c=1, ethanol)

SMILES

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CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

InChI

InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChIKey

RJKFOVLPORLFTN-LEKSSAKUSA-N

LogP

4.723500000000005

Topological Polar Surface Area

34.14 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

589

Safety Information

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GHS Hazard Pictograms

H351

Hazard Statement

H351 Suspected of causing cancer
Carcinogenicity

Stability

Stable. Incompatible with strong oxidizing agents.

Sensitiveness

sensitive to light

Synonyms & References

English

Progesterone
3,20-pregnene-4
4-pregnene-3,20-dione
beta-progesterone
corlutin
corlutina
corluvite
corporin
corpus luteum hormone
delta4-pregnene-3,20-dione
delta(sup4)-pregnene-3,20-dione
flavolutan
fologenon
gestone
gestormone
glanducorpin
hormoflaveine
hormoluton
lipolutin
lucorteum sol
luteal hormone
Lutein
luteinique
luteodyn
luteogan
luteohormone
luteol
luteosan
luteostab
luteovis
Lutex

MDL Number

MFCD00003658

Customs Code

29372390

FAQ

What is Pregn-4-ene-3,20-dione (CAS: 57-83-0)?

Pregn-4-ene-3,20-dione (CAS: 57-83-0) is a steroid compound with the chemical formula C21H30O2. It serves as a key intermediate in steroid hormone biosynthesis, featuring a pregnane ring system and two ketone groups. This compound is typically a white crystalline solid with low solubility in water. Its structural simplicity makes it valuable for research and industrial applications, while its reactivity influences its role in biochemical pathways and synthetic chemistry.

What are the main uses of Pregn-4-ene-3,20-dione (CAS: 57-83-0)?

Pregn-4-ene-3,20-dione (CAS: 57-83-0) is primarily used in pharmaceuticals as a precursor for corticosteroids and other steroid-derived drugs. In research, it aids in studying hormone metabolism and synthetic pathways. Industrially, it serves as a chemical intermediate for producing pharmaceuticals and cosmetics. Its applications also extend to veterinary medicine and as a reference standard in analytical chemistry, highlighting its versatility in various sectors.

Is Pregn-4-ene-3,20-dione (CAS: 57-83-0) safe?

Pregn-4-ene-3,20-dione (CAS: 57-83-0) is generally safe when handled properly, but it requires caution due to potential irritant properties. Safety standards emphasize avoiding skin contact and inhalation, with protective measures like gloves and ventilation recommended. While not classified as highly toxic, long-term exposure or ingestion should be avoided. Always follow OSHA guidelines and proper lab safety protocols for safe handling and disposal.

How should Pregn-4-ene-3,20-dione (CAS: 57-83-0) be stored?

Pregn-4-ene-3,20-dione (CAS: 57-83-0) should be stored in a cool, dry place (2-8°C), away from light and moisture. Use sealed, airtight containers to maintain stability and prevent degradation. Avoid exposure to air or reactive substances to ensure long-term preservation. Proper storage conditions are critical to maintaining its chemical integrity and safety, particularly in industrial and research settings.