Methyl L-serinate hydrochloride (1:1)

Basic Information

View in Editor

CAS Number

5680-80-8

Molecular Formula

C4H10ClNO3

Molecular Weight

155.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Solid

Melting Point

163 °C (dec.)

Boiling Point

234.7℃ at 760 mmHg

Flash Point

95.8℃

Specific Rotation

4.5 º (c=2, methanol)

SMILES

View in Editor

COC(=O)C(CO)N.Cl

InChI

InChI=1S/C4H9NO3.ClH/c1-8-4(7)3(5)2-6;/h3,6H,2,5H2,1H3;1H/t3-;/m0./s1

InChIKey

NDBQJIBNNUJNHA-DFWYDOINSA-N

LogP

-1.0992000000000002

Topological Polar Surface Area

72.55 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

83.4

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Moisture Sensitive

Synonyms & References

English

SCHEMBL159222
DTXSID801323780
H-Ser-OMe . HCl
(S)-Methyl 2-amino-3-hydroxypropanoate hydrochloride
serine methylester hydrochloride
S-2780
NS00082596
AKOS015892710
L-METHYL SERINATE HCL
CS-B1301
methyl serinate hydrochloride
(S)-serine methyl ester hydrochloride
AM82213
5680-80-8
L-Serine methyl ester hydrochloride
H-Ser-OMe.HCl
NDBQJIBNNUJNHA-DFWYDOINSA-N
L-Ser-OMe.HCl
methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride
Methyl L-serinate hydrochloride
serine methyl ester HCl
L-serine methyl ester, hydrochloride
(5)-serine methyl ester hydrochloride
l-serine methylate hydrochloride
serine methyl ester hydrochoride
B0267
L-serine methyl ester hydrochloric acid salt
(2-methoxy-2-oxoethyl)azanium;chloride
L-serine-methylester hydrochloride
L-Serine Methyl Ester Monohydrochloride
L-serine, methyl ester hydrochloride

MDL Number

MFCD00063680

Customs Code

29225000

FAQ

What is Methyl L-serinate hydrochloride (CAS: 5680-80-8)?

Methyl L-serinate hydrochloride (CAS: 5680-80-8) is a chiral compound formed by the esterification of L-serine with methanol and subsequent reaction with hydrochloric acid. Its chemical formula is C8H15NO5·HCl. It appears as a white crystalline solid, is soluble in water, and is commonly used in organic synthesis and pharmaceutical research due to its stereochemical properties.

What are the main uses of Methyl L-serinate hydrochloride (CAS: 5680-80-8)?

Methyl L-serinate hydrochloride (CAS: 5680-80-8) is primarily used in pharmaceuticals as a chiral intermediate for drug synthesis, including antihistamines and antipsychotics. It also serves in research for studying amino acid derivatives and in industrial applications for producing enantiomerically pure compounds. Potential uses in food additives or flavor enhancers are limited and require further validation.

Is Methyl L-serinate hydrochloride (CAS: 5680-80-8) safe?

Methyl L-serinate hydrochloride (CAS: 5680-80-8) is generally considered safe when handled properly. It may cause skin or eye irritation and is corrosive to metals, so protective measures like gloves, goggles, and ventilation are recommended. Safety data sheets (SDS) advise following standard chemical handling protocols to ensure compliance with OSHA and EPA regulations.

How should Methyl L-serinate hydrochloride (CAS: 5680-80-8) be stored?

Methyl L-serinate hydrochloride (CAS: 5680-80-8) should be stored in a cool, dry place (2-8°C), in airtight containers to prevent moisture absorption. It is light-sensitive, so storage in dark conditions is essential. Avoid exposure to high humidity or direct sunlight to maintain stability and prevent degradation over time.