Orteronel | CAS No. 566939-85-3

Orteronel

Basic Information

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CAS Number

566939-85-3

Molecular Formula

C18H17N3O2

Molecular Weight

307.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Density

1.35

SMILES

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CNC(=O)C1=CC2=C(C=C1)C=C(C=C2)C3(CCN4C3=CN=C4)O

InChI

InChI=1S/C18H17N3O2/c1-19-17(22)14-3-2-13-9-15(5-4-12(13)8-14)18(23)6-7-21-11-20-10-16(18)21/h2-5,8-11,23H,6-7H2,1H3,(H,19,22)/t18-/m0/s1

InChIKey

OZPFIJIOIVJZMN-SFHVURJKSA-N

LogP

2.0355000000000003

Topological Polar Surface Area

67.15 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

471

Synonyms & References

English

TAK-700 (S-form)
Orteronel
6-[(7S)-7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide
Tak 700
TAK-700
TAK-700-Orteronel
6-[(7S)-7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-2-naphthalenecarboxamide
UE5K2FNS92
TAK700
(S)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
6-((7S)-7-Hydroxy-6,7-dihydro-5H-pyrrolo(1,2-c)imidazol-7-yl)-N-methyl-2-naphthalenecarboxamide
Orteronel [USAN:INN]
6-[(7S)-7-HYDROXY-6,7-DIHYDRO-5H-PYRROLO[1,2-C]IMIDAZOL-7-YL]-N-METHYL-2-NAPHTHALENE
6-[(7S)-7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide
ORTERONEL [USAN]
EX-A159
CHEBI:231353
DB12066
(R)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
6-[(7S)-7-hydroxy-5H,6H,7H-pyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide
DTXSID001319121
SB16686
HMS3750I13
566939-85-3,Orteronel
CS-0580
6-[(7s)-7-hydroxy-6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-2-naphthamide
6-((7S)-7-hydroxy-6,7-dihydro-5H-pyrrolo(1,2-c)imidazol-7-yl)-N-methyl-2-naphthamide
6-[(7S)-6,7-dihydro-7-hydroxy-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-2-naphthalenecarboxamide
J-523835
566939-85-3
UNII-UE5K2FNS92

MDL Number

MFCD20528078

FAQ

What is Orteronel (CAS: 566939-85-3)?

Orteronel is a chemical compound with the CAS number 566939-85-3. It is a potent and selective inhibitor of farnesyltransferase, which is involved in the Ras protein prenylation pathway. Orteronel is known for its anti-cancer properties, particularly in treating prostate cancer.

What are the main uses of Orteronel (CAS: 566939-85-3)?

Orteronel is primarily used as a therapeutic agent in the treatment of prostate cancer. It is specifically indicated for patients with castration-resistant prostate cancer. Orteronel has shown promising results in clinical trials and is currently undergoing further research for additional applications.

Is Orteronel (CAS: 566939-85-3) safe?

Orteronel is generally considered safe when used under medical supervision. However, like any medication, it may cause side effects such as fatigue, nausea, and gastrointestinal issues. Patients should follow their healthcare provider's instructions and use the medication as prescribed to minimize risks and ensure safety.

How should Orteronel (CAS: 566939-85-3) be stored?

Orteronel should be stored in a tightly sealed container to protect it from moisture and light. It should be kept at room temperature (15-30°C) and away from direct sunlight and heat sources. Proper storage conditions are essential to maintain the efficacy and stability of the compound.