PIPES | CAS No. 5625-37-6

PIPES

Basic Information

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CAS Number

5625-37-6

Molecular Formula

C8H18N2O6S2

Molecular Weight

302.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

>300 °C

Boiling Point

°Cat760mmHg

Water Solubility

Soluble in water.

Solubility

0.1 M NaOH: 0.25 g/mL, clear, colorless

Refractive Index

1.6300 (estimate)

SMILES

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C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O

InChI

InChI=1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)

InChIKey

IHPYMWDTONKSCO-UHFFFAOYSA-N

LogP

-1.6203999999999958

pKa

6.8(at 25℃)

Topological Polar Surface Area

115.22000000000003 Å²

Hydrogen Bond Donor/Acceptor

2 / 8

Complexity

397

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1,4-piperazinebis(ethanesulphonic acid)
1,4-piperazine bis(ethanesulfonic acid)
Q7119420
PIPES, BioXtra, for molecular biology, >=99.5% (T)
EINECS 227-057-6
UNII-G502H79V6L
FT-0635789
F20299
C8H18N2O6S2
5-Cyclopropyl-2-ethyl-2H-pyrazole-3-carboxylicacid
W-105526
piperazine-n,n'-bis-(2-ethanesulphonic acid)
5625-37-6
Piperazine-1,4-bisethanesulfonic acid
PIPES, free acid
SCHEMBL63679
HY-D0875
2,2'-(Piperazine-1,4-diyl)diethanesulfonicacid
2-[4-(2-sulfoethyl)piperazin-1-yl]ethane-1-sulfonic acid
NS00033488
NSC-157117
2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid
PIPES, BioXtra, >=99% (titration)
2-[4-(2-sulfonatoethyl)piperazine-1,4-diium-1-yl]ethanesulfonate
1,4-Piperazinediethanesulfonic acid
PIPES, BioPerformance Certified, suitable for cell culture, >=99%
AMY23365
PIPES, >=99% (titration)
CS-0015185
Piperazine-1,4-bis(2-ethanesulfonic acid)
piperazine-N

MDL Number

MFCD00006159

Customs Code

29335995

FAQ

What is PIPES (CAS: 5625-37-6)?

PIPES, or 1,4-piperazinediethanesulfonic acid, is a zwitterionic buffer commonly used in biochemical applications. It has the chemical formula C6H14N2O5S and is known for its high buffering capacity in the physiological pH range. PIPES is a white crystalline solid that is soluble in water and has a low toxicity profile when used properly.

What are the main uses of PIPES (CAS: 5625-37-6)?

PIPES is widely used in pharmaceuticals, biochemistry, and molecular biology for maintaining stable pH conditions. It serves as a buffer in enzyme assays, cell culture media, and as a component in the preparation of fluorescent dyes and other reagents. Additionally, it finds applications in the food industry for pH control in certain processing steps.

Is PIPES (CAS: 5625-37-6) safe?

PIPES is considered safe when handled according to standard laboratory practices. It has low toxicity and is not classified as a harmful substance under most safety regulations. However, protective measures such as gloves and eye protection are recommended during handling to minimize direct contact and ensure safe use in various applications.

How should PIPES (CAS: 5625-37-6) be stored?

PIPES should be stored in a cool, dry place away from direct light. It is typically kept in airtight containers to prevent moisture absorption and degradation. The optimal storage temperature is below 25°C, and it should be protected from humidity to maintain its chemical stability and effectiveness.