Cefuroxime sodium

Basic Information

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CAS Number

56238-63-2

Molecular Formula

C16H15N4NaO8S

Molecular Weight

446.4 g/mol

Basic Physical Properties

Melting Point

240-245°C(dec)

Water Solubility

Freely soluble in water

Specific Rotation

D20 +60° (c = 0.91 in water)

SMILES

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CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)[O-].[Na+]

InChI

InChI=1S/C16H16N4O8S.Na/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20;/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24);/q;+1/p-1/b19-9-;/t10-,14-;/m1./s1

InChIKey

URDOHUPGIOGTKV-JTBFTWTJSA-M

LogP

-0.84160

pKa

pKa (water): 2.5; (DMF): 5.1(at 25℃)

Complexity

804

Safety Information

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GHS Hazard Pictograms

H317

H334

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Synonyms & References

English

Zinacef (TN)
C08108
Bioxima
CEFUROXIME SODIUM [USP-RS]
Cefuroxim MN
Cefumax
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)acetyl)amino)-8-oxo-, monosodium salt (6R-(6alpha,7beta(Z)))-
CEFUROXIME SODIUM [EP IMPURITY]
CEFUROXIME SODIUM IN PLASTIC CONTAINER
CEFUROXIME SODIUM [WHO-DD]
CEFUROXIME SODIUM (USP MONOGRAPH)
Kefurox
Froxal
Cefuroxime sodium, United States Pharmacopeia (USP) Reference Standard
CEFUROXIME SODIUM
CEFUROXIME SODIUM [VANDF]
Cefuroxime sodium 100 microg/mL in Acetonitrile/Water
Cefuroxime for Injection and Dextrose for Injection in Duplex Container
HMS2097O21
Cefuroxim Fresenius
Cefuroxim curasan
CEFUROXIME SODIUM (USP-RS)
CS-4733
Cefurex
CEFUROXIME SODIUM [USP MONOGRAPH]
s4620
Cetroxil
Cefuroxim Hexal
Sodium (6R,7R)-7-(2-(2-furyl)glyoxylamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, 7(sup 2)-(Z)-(O-methyloxime), carbamate (ester)
MLS000069576
Zinnat (inj.)

MDL Number

MFCD09878727

Customs Code

2941905990

FAQ

What is Cefuroxime sodium (CAS: 56238-63-2)?

Cefuroxime sodium is a semi-synthetic broad-spectrum antibiotic belonging to the cephalosporin class. It is used primarily for its antibacterial properties and is commonly available as a sodium salt. Its chemical formula is C16H17N5O4S2Na, and it is known for its stability in aqueous solutions. Cefuroxime sodium exhibits good solubility in water and is often formulated for oral or injectable use.

What are the main uses of Cefuroxime sodium (CAS: 56238-63-2)?

Cefuroxime sodium is mainly used in the treatment of bacterial infections such as respiratory tract infections, skin infections, and urinary tract infections. It is also employed in veterinary medicine and as a research compound for studying antibiotic mechanisms. Due to its broad-spectrum activity, it is effective against a variety of Gram-positive and Gram-negative bacteria, making it a valuable pharmaceutical agent.

Is Cefuroxime sodium (CAS: 56238-63-2) safe?

Cefuroxime sodium is generally considered safe when used as directed. It is approved for human and veterinary use by regulatory agencies. However, like all antibiotics, it may cause side effects such as gastrointestinal discomfort or allergic reactions. Proper handling and adherence to safety guidelines are essential to ensure safe use and prevent contamination.

How should Cefuroxime sodium (CAS: 56238-63-2) be stored?

Cefuroxime sodium should be stored in a cool, dry place away from direct light. It is typically kept in airtight containers to maintain its stability and prevent moisture exposure. The recommended storage temperature is between 2°C to 8°C. Always check the expiration date and ensure proper labeling to maintain quality and safety.