methyl 2-amino-3-hydroxypropanoate hydrochloride

Basic Information

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CAS Number

5619-04-5

Molecular Formula

C4H10ClNO3

Molecular Weight

155.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

134-136 °C

Density

0.8600

Flash Point

95.8℃

SMILES

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COC(=O)C(CO)N.Cl

InChI

InChI=1S/C4H9NO3.ClH/c1-8-4(7)3(5)2-6;/h3,6H,2,5H2,1H3;1H

InChIKey

NDBQJIBNNUJNHA-UHFFFAOYSA-N

LogP

-1.0992000000000002

Topological Polar Surface Area

72.55 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

83.4

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Moisture Sensitive

Synonyms & References

English

SY005975
DL serine methyl ester hydrochloride
EINECS 227-047-1
5619-04-5
NSC84252
SB40719
methyl 2-amino-3-hydroxypropanoate;hydrochloride
methyl 2-amino-3-hydroxypropanoate hydrochloride
FT-0628014
Methyl DL-serinate hydrochloride
SY005340
NSC-84252
Methyl serinate--hydrogen chloride (1/1)
H-DL-Ser-OMe.HCl
DL-serine methylester HCl
MFCD00066121
S0576
DL-Serine methyl ester hydrochloride
dl-serinemethylester hydrochloride
F0001-1475
EC 227-047-1
5819-04-5
MFCD00012593
HY-W013622
3-hydroxy-1-methoxy-1-oxopropan-2-aminium chloride
methyl 2-amino-3-hydroxypropanoate hydrochloride salt
Methyl DL-serinate HCl
2-Amino-3-hydroxy-propionic acid methyl ester; hydrochloride
PB43113
AKOS009031553
SCHEMBL159221

MDL Number

MFCD00012593

Customs Code

29225000

FAQ

What are the physical and chemical properties of methyl 2-amino-3-hydroxypropanoate hydrochloride (CAS: 5619-04-5)?

Methyl 2-amino-3-hydroxypropanoate hydrochloride (CAS: 5619-04-5) is a crystalline white powder with a molecular weight of approximately 172.69 g/mol. It is slightly soluble in water and ethanol and is highly soluble in chloroform. The compound is moderately reactive, particularly in basic conditions, and can be used as a chiral building block in organic synthesis.

How is methyl 2-amino-3-hydroxypropanoate hydrochloride (CAS: 5619-04-5) typically synthesized?

Methyl 2-amino-3-hydroxypropanoate hydrochloride (CAS: 5619-04-5) can be synthesized via the reaction of 2-amino-3-hydroxypropionic acid with methyl chloroformate in the presence of a suitable base like triethylamine. The process yields a high purity product with good selectivity and a theoretical yield of up to 90%.

What industries use methyl 2-amino-3-hydroxypropanoate hydrochloride (CAS: 5619-04-5)?

Methyl 2-amino-3-hydroxypropanoate hydrochloride (CAS: 5619-04-5) is primarily used in the pharmaceutical industry for the synthesis of chiral intermediates. It is also utilized in the production of certain polymers and as a reagent in analytical chemistry for the development of sensors and semiconductors.

What precautions should be taken when handling methyl 2-amino-3-hydroxypropanoate hydrochloride (CAS: 5619-04-5)?

When handling methyl 2-amino-3-hydroxypropanoate hydrochloride (CAS: 5619-04-5), it is recommended to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risk. In the event of a spill, use appropriate spill cleanup materials and refer to the safety data sheet (SDS) for detailed instructions.