Acarbose (Acarbosum) (Mixture of Diastereomers)

Basic Information

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CAS Number

56180-94-0

Molecular Formula

C25H43NO18

Molecular Weight

645.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

124-126°C

Boiling Point

971.6°C at 760 mmHg

Density

1.4278 (rough estimate)

Water Solubility

Soluble in water.

Flash Point

541.4 °C

Solubility

In water, 1.0X10+6 mg/L /miscible/ at 25 °C (est)

Refractive Index

1.6000 (estimate)

Specific Rotation

+173° to +183° (c=1, H2O)

SMILES

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C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1N[C@H]3C=C(CO)[C@@H](O)[C@H](O)[C@H]3O

InChI

InChI=1S/C25H43NO18/c1-7-13(26-9-2-8(3-27)14(33)18(37)15(9)34)17(36)20(39)24(41-7)44-23-12(6-30)42-25(21(40)19(23)38)43-22(11(32)5-29)16(35)10(31)4-28/h2,4,7,9-27,29-40H,3,5-6H2,1H3/t7-,9+,10+,11-,12-,13-,14-,15+,16-,17+,18+,19-,20-,21-,22-,23-,24-,25-/m1/s1

InChIKey

CEMXHAPUFJOOSV-XGWNLRGSSA-N

LogP

-8.721900000000014

Topological Polar Surface Area

329.01 Å²

Hydrogen Bond Donor/Acceptor

14 / 19

Complexity

962

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Synonyms & References

English

acarbose
bay-g5421
d-glucose,o-4,6-dideoxy-4-(((1s-(1-alpha,4-alpha,5-beta,6-alpha))-4,5,6-trihyd
roxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-alpha-d-glucopyranosyl-(1-4)-o
5-[5-[3,4-DIHYDROXY-6-METHYL-5-[[4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-1-CYCLOHEX-2-ENYL]AMINO]OXAN-2-YL]OXY-3,4-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY-6-(HYDROXYMETHYL)OXANE-2,3,4-TRIOL
Glucobay
Acarbose Hydrate
O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHY
acarviostatin I01
Ascarbose
Prandase
Precos
Precose
4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose
Sugammadex sodium Impurity
acarbose iMpurity
Beta-Acarbose
XUFXOAAUWZOOIT-SXARVLRPSA-N
DSSTox_RID_81300
DSSTox_CID_26034
DSSTox_GSID_46034
Arcabose
Glucor
1agm
1ukt
QPS
Acarbose, >=95%
HMC-(1-4)AGL-(1-4)GLC-(1-4)GLC
GTPL6791
HMS3677P19
HMS3413P19

MDL Number

MFCD30478372

Customs Code

29400090

FAQ

What is Acarbose (Acarbosum) (CAS: 56180-94-0)?

Acarbose (Acarbosum) is a carbohydrate-based medication used primarily for the management of type 2 diabetes. It works by inhibiting the enzyme alpha-glucosidase, which slows the digestion of carbohydrates and reduces postprandial blood glucose levels. The compound is a mixture of diastereomers and has the molecular formula C12H22O12.

What are the main uses of Acarbose (Acarbosum) (CAS: 56180-94-0)?

Acarbose is mainly used in pharmaceuticals to treat type 2 diabetes. It helps regulate blood sugar levels by slowing the breakdown of complex carbohydrates. Additionally, it is used in research for studying carbohydrate metabolism and in some industrial applications related to enzyme inhibition and food processing.

Is Acarbose (Acarbosum) (CAS: 56180-94-0) safe?

Acarbose is generally considered safe when used as directed. It is well-tolerated by most patients, though some may experience gastrointestinal side effects. Safety standards for Acarbose include adherence to proper handling and storage protocols to prevent contamination. Always follow medical advice and safety guidelines when using this compound.

How should Acarbose (Acarbosum) (CAS: 56180-94-0) be stored?

Acarbose should be stored in a cool, dry place away from direct sunlight. It is typically kept at a temperature between 15°C to 30°C (59°F to 86°F) and in a tightly sealed container to maintain stability and prevent moisture exposure. Proper storage helps preserve its efficacy and safety.