Chlorhexidine diacetate

Basic Information

View in Editor

CAS Number

56-95-1

Molecular Formula

C26H38Cl2N10O4

Molecular Weight

625.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

153.0 to 160.0 deg-C

Boiling Point

699.3°C at 760 mmHg

Water Solubility

1.9 g/100 mL (20 ºC)

Flash Point

376.7°C

Solubility

H2O: 15 mg/mL, clear

SMILES

View in Editor

N=C(NC(=N)Nc1ccc(cc1)Cl)NCCCCCCNC(=N)NC(=N)Nc1ccc(cc1)Cl.CC(=O)O.CC(=O)O

InChI

InChI=1S/C22H30Cl2N10.2C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H3,(H,3,4)

InChIKey

WDRFFJWBUDTUCA-UHFFFAOYSA-N

LogP

4.357080000000002

Topological Polar Surface Area

242.17999999999998 Å²

Hydrogen Bond Donor/Acceptor

12 / 14

Complexity

680

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H410

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 9 Class 9

Toxicity

LD50 orally in mice: 2 g/kg (Davies)

Synonyms & References

English

CHLOROHEXIDINE ACETATE
1,1'-HEXAMETHYLENEBIS[5-(4-CHLORO-PHENYL)BIGUANIDE] DIACETATE MONOHYDRATE
1,1'-HEXAMETHYLENEBIS[5-(P-CHLOROPHENYL)BIGUANIDE]) DIACETATE SALT
1,6-BIS[N5-(P-CHLOROPHENYL)-N1-BIGUANIDO]HEXANE DIACETATE SALT
1,6-BIS(N-P-CHLOROPHENYLDIGUANIDO)HEXANE DIACETATE
1,6-DI(N-P-CHLOROPHENYL-DIGUANIDO) HEXANE DIACETATE
CHLORHEXIDINE ACETATE
CHLORHEXIDINE DIACETATE
CHLORHEXIDINE DIACETATE MONOHYDRATE
CHLORHEXIDINE DIACETATE SALT
HIBITANE DIACETATE
1,1’-hexamethylenebis(5-(p-chlorophenyl)-biguaniddiacetate
1,1’-hexamethylenebis(5-(p-chlorophenyl)biguanide)diacetate
1,6-bis(5-(p-chlorophenyl)biguandino)hexanediacetate
1,6-di(4’-chlorophenyldiguanidino)hexanediacetate
10,040diacetate
2,4,11,13-Tetraazatetradecanediimidamide,N,N’’-bis(4-chlorophenyl)-3,12-diimino-,diacetate
Hibitaneacetate
N,N’’-Bis(4-Chlorophenyl)-3,12-diimino-2,4-11,13-tetraazatetradcanediimidamide
Chlorhexidine diacetate salt hydrate
acetic acid,(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
CHLORHEXIDINE DIACETATE BP2007
Chlorhexidine diacetate salt monohydrate
1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] Diacetate
Chlorhexidine di(acetate)
1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane
1,1'-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
Chlorhexidine acetate (chlorhexidine acetate)
药用醋酸氯己定原料药生产厂家
Nolvasan
Bactigras

MDL Number

MFCD00150042

FAQ

What is Chlorhexidine diacetate (CAS: 56-95-1)?

Chlorhexidine diacetate (CAS: 56-95-1) is an antiseptic compound used for its antimicrobial properties. It is a white, water-soluble powder with the chemical formula C22H30Cl2N4O4. Known for its broad-spectrum activity against bacteria, fungi, and viruses, it is commonly formulated into mouthwashes, topical antiseptics, and wound care products. Its cationic structure allows it to bind to microbial cell membranes, disrupting their function and preventing infection.

What are the main uses of Chlorhexidine diacetate (CAS: 56-95-1)?

Chlorhexidine diacetate (CAS: 56-95-1) is primarily used in pharmaceuticals as an antiseptic for oral care, skin disinfection, and wound healing. It also finds applications in industrial settings for surface sterilization and in food processing as a preservative. In research, it is employed to study antimicrobial mechanisms. Its efficacy against both gram-positive and gram-negative bacteria makes it a key ingredient in medical and hygiene products.

Is Chlorhexidine diacetate (CAS: 56-95-1) safe?

Chlorhexidine diacetate (CAS: 56-95-1) is generally safe when used as directed, with low toxicity and minimal systemic absorption. However, prolonged use may cause skin irritation or allergic reactions. It is approved by regulatory bodies like the FDA and EMA for topical applications. Handling precautions include avoiding eye contact and ingestion, and using gloves when applying. Proper dilution and adherence to safety guidelines ensure safe use in medical and consumer products.

How should Chlorhexidine diacetate (CAS: 56-95-1) be stored?

Chlorhexidine diacetate (CAS: 56-95-1) should be stored in a cool, dry place away from moisture and light. Keep in a sealed container to maintain stability and prevent contamination. Avoid exposure to extreme temperatures (ideally below 25°C) and ensure proper ventilation. Storage conditions should comply with safety standards to preserve efficacy and prevent degradation over time.