Betamethasone Dipropionate

Basic Information

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CAS Number

5593-20-4

Molecular Formula

C28H37FO7

Molecular Weight

504.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

Powder

Melting Point

175.0 to 179.0 deg-C

Boiling Point

622.9°C at 760 mmHg

Flash Point

318.6°C

Refractive Index

69 ° (C=1, Dioxane)

Specific Rotation

+66.0-+72.0° (c=1, Dioxane)

SMILES

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CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CC

InChI

InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3

InChIKey

CIWBQSYVNNPZIQ-UHFFFAOYSA-N

LogP

3.8175000000000026

Topological Polar Surface Area

106.97 Å²

Hydrogen Bond Donor/Acceptor

1 / 7

Complexity

1050

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

Sch-11460
(11beta,16beta)-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate
BETAMETHASONE DIPROPIONATE [EP MONOGRAPH]
CS-7549
CHEMBL1200384
BDBM50421892
BETAMETHASONE DIPROPIONATE [WHO-DD]
LOTRISONE COMPONENT BETAMETHASONE DIPROPIONATE
BRN 3638108
NCGC00159443-01
BETAMETHASONE DIPROPIONATE (EP MONOGRAPH)
Diprospan
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-.beta.,17,21-trihydroxy-16-.beta.-methyl-,17,21-dipropionate
Alphatrex
D01637
AB01274713_02
DTXCID302672
.beta.-Methasone 17,21-dipropionate
BETAMETHASONE DIPROPIONATE
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11.beta.,16.beta.)-
9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate)
BETAMETHASONE DIPROPIONATE (USP-RS)
BETAMETHASONE DIPROPIONATE [USP MONOGRAPH]
BETAMETHASONE 17.ALPHA.,21-DIPROPIONATE
BETAMETHASONE DIPROPIONATE [JAN]
9-Fluoro-11.beta.-hydroxy-16.beta.-methyl-3,20-dioxo-17-(propionyloxy)pregna-1,4-dien-21-yl propionate #
SCHEMBL7519
component of Alphatrex (Salt/Mix)
2-((2S,10S,11S,13S,15S,17S,1R,14R)-1-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxo -14-propanoyloxytetracyclo[8.7.0.0<2,7>.0<11,15>]heptadeca-3,6-dien-14-yl)-2-o xoethyl propanoate
9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate
WYNZORA COMPONENT BETAMETHASONE DIPROPIONATE

MDL Number

MFCD00072035

FAQ

What is Betamethasone Dipropionate (CAS: 5593-20-4)?

Betamethasone Dipropionate (CAS: 5593-20-4) is a synthetic corticosteroid used for its potent anti-inflammatory and immunosuppressive properties. Its chemical formula is C25H32O7, and it is a white crystalline powder with low solubility in water but moderate solubility in alcohol. It is commonly prescribed for treating skin conditions and is classified as a glucocorticoid hormone.

What are the main uses of Betamethasone Dipropionate (CAS: 5593-20-4)?

Betamethasone Dipropionate (CAS: 5593-20-4) is primarily used in dermatology for topical treatments of eczema, psoriasis, dermatitis, and other inflammatory skin disorders. It is also employed in systemic formulations for managing autoimmune diseases and allergic reactions. Its applications include reducing swelling, itching, and redness in various medical and research contexts.

Is Betamethasone Dipropionate (CAS: 5593-20-4) safe?

Betamethasone Dipropionate (CAS: 5593-20-4) is safe when used as directed by healthcare professionals. However, prolonged use may cause skin thinning, acne, or adrenal suppression. Safety guidelines emphasize avoiding eye contact, using protective gloves during handling, and adhering to prescribed dosages. It is regulated by the FDA and EPA for controlled use in pharmaceuticals.

How should Betamethasone Dipropionate (CAS: 5593-20-4) be stored?

Betamethasone Dipropionate (CAS: 5593-20-4) should be stored in a cool, dry place (2-8°C), protected from light and moisture. Keep the container tightly closed to prevent contamination. Avoid exposure to heat and direct sunlight to maintain stability. Proper storage ensures efficacy and compliance with pharmaceutical safety standards.