5-Bromo-2-ethoxypyridine

Basic Information

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CAS Number

55849-30-4

Molecular Formula

C7H8BrNO

Molecular Weight

202.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

35.0 to 39.0 deg-C

Boiling Point

107°C/33mmHg

SMILES

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CCOC1=NC=C(C=C1)Br

InChI

InChI=1S/C7H8BrNO/c1-2-10-7-4-3-6(8)5-9-7/h3-5H,2H2,1H3

InChIKey

WQXZKMUZWPUZGL-UHFFFAOYSA-N

LogP

2.2428

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

99.6

Safety Information

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GHS Hazard Pictograms

H302

H315

H317

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

SCHEMBL156935
5-bromo-ethoxy-pyridine
55849-30-4
WQXZKMUZWPUZGL-UHFFFAOYSA-N
B3673
A8062
DTXSID50355774
2-ethoxy-5-bromopyridine
MFCD00234311
AC-907/25004667
5-bromo-2-ethoxy-pyridine
Pyridine, 5-bromo-2-ethoxy-
3-BROMO-6-ETHOXYPYRIDINE
FT-0640343
5-Bromo-2-ethoxypyridine, 97%
J-516916
AM20070041
AB05210
DS-0799
CS-0014710
EN300-225185
AC-5974
SY018882
5-Bromo-2-ethoxypyridine
5-bromo-2-(ethyloxy)pyridine
FS-1790
AKOS005199250
2-Ethoxy-5-bromopyridine
5-Bromo-2-ethoxy-pyridine
2-ethoxy-5-bromo-pyridine
3-bromo-6-ethoxy-pyridine

MDL Number

MFCD00234311

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Bromo-2-ethoxypyridine (CAS: 55849-30-4)?

5-Bromo-2-ethoxypyridine (CAS: 55849-30-4) is a crystalline solid with a molecular weight of approximately 213.11 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is a key intermediate in the synthesis of various pharmaceuticals and organic compounds.

How is 5-Bromo-2-ethoxypyridine (CAS: 55849-30-4) typically synthesized?

5-Bromo-2-ethoxypyridine is typically synthesized by bromination of 2-ethoxypyridine using bromine in the presence of a Lewis acid catalyst like aluminum bromide (AlBr3). The reaction yields a high purity product with a moderate to good yield, depending on the reaction conditions and optimization.

What industries use 5-Bromo-2-ethoxypyridine (CAS: 55849-30-4)?

5-Bromo-2-ethoxypyridine (CAS: 55849-30-4) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also utilized in the chemical industry for the development of organic semiconductors and as a component in some polymer formulations.

What precautions should be taken when handling 5-Bromo-2-ethoxypyridine (CAS: 55849-30-4)?

When handling 5-Bromo-2-ethoxypyridine (CAS: 55849-30-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate absorbent materials, and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.