5-Bromo-2-ethoxypyridine(CAS: 55849-30-4)

5-Bromo-2-ethoxypyridine (CAS: 55849-30-4) is a crystalline solid with a molecular weight of approximately 213.11 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is a key intermediate in the synthesis of various pharmaceuticals and organic compounds.

5-Bromo-2-ethoxypyridine is typically synthesized by bromination of 2-ethoxypyridine using bromine in the presence of a Lewis acid catalyst like aluminum bromide (AlBr3). The reaction yields a high purity product with a moderate to good yield, depending on the reaction conditions and optimization.

5-Bromo-2-ethoxypyridine (CAS: 55849-30-4) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also utilized in the chemical industry for the development of organic semiconductors and as a component in some polymer formulations.

When handling 5-Bromo-2-ethoxypyridine (CAS: 55849-30-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate absorbent materials, and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.