Betahistine DiHCl

Basic Information

View in Editor

CAS Number

5579-84-0

Molecular Formula

C8H14Cl2N2

Molecular Weight

209.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

150-154 ºC

Boiling Point

210.9°C at 760 mmHg

Density

0.9670

Flash Point

96.7 °C

SMILES

View in Editor

CNCCC1=CC=CC=N1.Cl.Cl

InChI

InChI=1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H

InChIKey

XVDFMHARQUBJRE-UHFFFAOYSA-N

LogP

1.6871

Topological Polar Surface Area

24.92 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

83.3

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Sensitive to humidity & light.

Synonyms & References

English

Betahistine hydrochloride (USP)
SY066662
NCGC00095910-01
Betahistine dihydrochloride
Betahistine hydrochloride [USAN:USP]
2-[2-(Methylamino)ethyl]pyridine dihydrochloride
beta-Histine dihdrochloride
CHEMBL1446813
BCP13779
Methyl[2-(2-pyridyl)ethyl]amine dihydrochloride
EN300-31560
UNII-49K58SMZ7U
2-(2-(Methylamino)ethyl)pyridine dihydrochloride
Betahistine Di HCl
BETAHISTINE DIHYDROCHLORIDE [MI]
AMY40800
NSC 757397
s3176
BETAHISTINE HYDROCHLORIDE [MART.]
NS00076172
Betahistine hydrochloride
HY-B0524A
SCHEMBL60646
CCG-40327
BETAHISTINE DIHYDROCHLORIDE [EP MONOGRAPH]
MFCD00012813
BETAHISTINE HYDROCHLORIDE [USP-RS]
N-methyl-N-(2-pyridin-2-ylethyl)amine dihydrochloride
SPECTRUM1500670
49K58SMZ7U
SW196969-3

MDL Number

MFCD00012813

Customs Code

2933399090

FAQ

What is Betahistine DiHCl (CAS: 5579-84-0)?

Betahistine dihydrochloride (Betahistine DiHCl, CAS: 5579-84-0) is a compound used in the treatment of vertigo and Meniere's disease. It is a structural analog of histamine with selective agonist activity at H1 receptors, particularly in the vestibular system. Its molecular formula is C15H22Cl2N2O2. It is a white to off-white crystalline powder with poor solubility in water but soluble in acidic solutions.

What are the main uses of Betahistine DiHCl (CAS: 5579-84-0)?

Betahistine dihydrochloride (CAS: 5579-84-0) is primarily used in the treatment of vertigo and Meniere's disease. It is also used in the prevention of motion sickness and in research as a pharmacological tool to study histamine receptor function and signaling pathways in the central nervous system.

Is Betahistine DiHCl (CAS: 5579-84-0) safe?

Betahistine dihydrochloride (CAS: 5579-84-0) is generally considered safe when used as directed for the treatment of vertigo and Meniere's disease. However, it may cause side effects such as palpitations, nausea, and headache. Patients should follow the prescription and avoid driving or operating machinery if they experience dizziness. Proper storage and handling should also be followed to minimize potential risks.

How should Betahistine DiHCl (CAS: 5579-84-0) be stored?

Betahistine dihydrochloride (CAS: 5579-84-0) should be stored in a tightly closed container to protect it from light. It should be kept in a cool, dry place, preferably at room temperature (15-30°C) and away from excessive heat and humidity. Avoid exposure to direct sunlight and store it in a place that is not accessible to children and pets.