Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E) | CAS No. 5534-09-8
Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E)
Basic Information
CAS Number
5534-09-8
Molecular Formula
C28H37ClO7
Molecular Weight
521.05 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
205-209°C
Boiling Point
630.5°C at 760 mmHg
Flash Point
335.1 °C
Refractive Index
1.4429 (estimate)
Specific Rotation
+88° - +94° (c=1, Dioxane)
Safety Information
View Safety InformationGHS Hazard Pictograms
H361Hazard Statement
H361
Suspected of damaging fertility or the unborn child
Reproductive toxicity
Reproductive toxicity
Synonyms & References
English
- NCGC00179392-01
- 9alpha-chloro-16beta-methyl-3,20-dioxo-1,4-pregnadiene-11beta,17,21-triol 17,21-dipropionate
- BECLOMETASONE DIPROPIONATE [WHO-IP]
- BECLOMETASONI DIPROPIONAS [WHO-IP LATIN]
- Tox21_113168
- Qnasl (TN)
- QVAR REDIHALER
- Sanasthmyl
- QVAR 40
- Pregna-1,4-diene-3,20-dione, 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-, 17,21-dipropionate
- GTPL5894
- ORBESHIELD
- Sanasthymyl
- Beclometasone dipropionate for peak identification, European Pharmacopoeia (EP) Reference Standard
- Sanasthmax
- HMS3259H03
- Aldecin
- Vanceril
- Atomase
- Entyderma
- BECLOMETHASONE DIPROPIONATE [MI]
- CAS-5534-09-8
- NS00000089
- HY-13571A
- BECLOMETHASONE DIPROPIONATE (USP-RS)
- BECLOMETHASONE DIPROPIONATE [VANDF]
- Becodisks
- Prestwick1_000855
- 2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl propanoate
- Spir
- Propaderm Forte
MDL Number
MFCD00135613
Customs Code
2937290090
FAQ
What is Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E) (CAS: 5534-09-8)?
Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E), with CAS number 5534-09-8, is a corticosteroid compound classified as an impurity in the European Pharmacopoeia (EP). It is a white to off-white crystalline powder, soluble in ethanol and methanol, and exhibits anti-inflammatory and immunosuppressive properties. This compound is a derivative of betamethasone, commonly used in pharmaceuticals, but its presence as an impurity requires careful monitoring during drug production.
What are the main uses of Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E) (CAS: 5534-09-8)?
Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E) is primarily used in pharmaceutical quality control to ensure the purity of corticosteroid drugs. It serves as a reference standard for analytical testing and is also employed in research to study impurity profiles. Although not intended for direct therapeutic use, it plays a critical role in drug development and regulatory compliance, particularly in identifying trace contaminants in formulations.
Is Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E) (CAS: 5534-09-8) safe?
Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E) is not intended for human or animal use but is considered safe in controlled laboratory and manufacturing environments when handled properly. Safety precautions include wearing protective gloves and eyewear, ensuring adequate ventilation, and adhering to standard operating procedures. Regulatory guidelines emphasize its role as a non-therapeutic impurity, requiring strict containment to prevent contamination of final products.
How should Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E) (CAS: 5534-09-8) be stored?
Beclomethasone Dipropionate (Betamethasone Dipropionate EP Impurity E) should be stored in a cool, dry, and dark place, ideally at 2-8°C, to maintain stability. It must be kept in a sealed container to prevent moisture absorption and degradation. Avoid exposure to light, air, and incompatible substances. Storage conditions should comply with pharmaceutical standards to ensure product integrity and safety during handling and analysis.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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