1-(2-Hydroxy-4-methoxyphenyl)ethanone

Basic Information

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CAS Number

552-41-0

Molecular Formula

C9H10O3

Molecular Weight

166.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

48-50 °C

Boiling Point

154°C/20mmHg

Solubility

Methanol,Chloroform,Ethyl Acetate,DMSO

Refractive Index

1.5452 (estimate)

SMILES

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COc1ccc(C(=O)C)c(O)c1

InChI

InChI=1S/C9H10O3/c1-6(10)8-4-3-7(12-2)5-9(8)11/h3-5,11H,1-2H3

InChIKey

UILPJVPSNHJFIK-UHFFFAOYSA-N

LogP

1.6034

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

167

Safety Information

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GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Synonyms & References

English

1-(2-Hydroxy-4-methoxyphenyl)ethanone
1-(2-hydroxy-4-methoxyphenyl)-ethanon
2’-hydroxy-4’-methoxy-acetophenon
4-o-methylresacetophenone
Acetophenone, 2'-hydroxy-4'-methoxy-
Paeonal
resacetophenone,4-o-methylester
Resacetophenone-4-methyl ether
2'-Hydroxy-4'-methoxyacetophenone
Paeonolum
2′-Hydroxy-4′-methoxyacetophenone
2-HYDROXY-4-METHOXYACETOPHENONE
Resacetophenone 4-O-methyl ether
Paeonol
1-(2-hydroxy-4-methoxyphenyl)ethan-1-one
[ "" ]
Danpiphol
Peonol
Ethanone, 1-(2-hydroxy-4-methoxyphenyl)-
4-Methoxy-2-hydroxyacetophenone
Resacetophenone, 4-O-methyl ester
4'-Methoxy-2'-hydroxyacetophenone
1-(2-hydr
Peonol,Paeonolum,Resacetophenone 4-O-methyl ether,Paeono,Paconol,2-Hydroxy-4-methoxyphenyl methyl ke...

MDL Number

MFCD00008730

Customs Code

2914509090

FAQ

What is 1-(2-Hydroxy-4-methoxyphenyl)ethanone (CAS: 552-41-0)?

1-(2-Hydroxy-4-methoxyphenyl)ethanone (CAS: 552-41-0) is an aromatic ketone compound with the chemical formula C9H10O3. It features a benzene ring substituted with hydroxy and methoxy groups, linked to an acetyl moiety. Known for its stability and solubility in organic solvents, this compound is commonly used in organic synthesis. Its molecular structure makes it a key intermediate in pharmaceutical and agrochemical research. The compound is odorless and typically appears as a white solid or liquid, depending on purity and conditions.

What are the main uses of 1-(2-Hydroxy-4-methoxyphenyl)ethanone (CAS: 552-41-0)?

1-(2-Hydroxy-4-methoxyphenyl)ethanone (CAS: 552-41-0) is widely used in pharmaceuticals as a building block for drug development, particularly in creating derivatives with antioxidant or anti-inflammatory properties. It also serves in agrochemicals and dye synthesis. In research, it aids in developing new materials and organic compounds. Its versatility in functional group modification makes it valuable for industrial applications, including polymer science and flavor chemistry. The compound’s reactivity supports its role in various chemical reactions.

Is 1-(2-Hydroxy-4-methoxyphenyl)ethanone (CAS: 552-41-0) safe?

1-(2-Hydroxy-4-methoxyphenyl)ethanone (CAS: 552-41-0) is generally considered safe when handled properly. However, it may cause skin or eye irritation. Safety precautions include wearing gloves, goggles, and a lab coat to minimize exposure. Ensure proper ventilation to avoid inhalation risks. While not classified as highly toxic, adherence to OSHA and EPA guidelines is recommended. Avoid contact with heat or open flames due to its potential flammability. Always follow safety data sheet (SDS) instructions for safe handling.

How should 1-(2-Hydroxy-4-methoxyphenyl)ethanone (CAS: 552-41-0) be stored?

1-(2-Hydroxy-4-methoxyphenyl)ethanone (CAS: 552-41-0) should be stored in a sealed, airtight container in a cool (2-8°C), dry place, away from light. Maintain humidity below 60% to prevent degradation. Store in a well-ventilated area to avoid inhalation of vapors. Keep away from heat sources and open flames due to its flammability. Ensure proper labeling and storage in a chemical storage cabinet to maintain stability and safety.