2-Nitrobenzoic acid

Basic Information

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CAS Number

552-16-9

Molecular Formula

C7H5NO4

Molecular Weight

167.12 g/mol

EINECS

209-004-9

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Off-white

Melting Point

146-148 °C

Boiling Point

295.67°C (rough estimate)

Density

1,58 g/cm3

Water Solubility

6.8 g/L

Flash Point

157.5℃

Solubility

7.8g/l

Refractive Index

1.6280 (estimate)

SMILES

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C1=CC=C(C(=C1)C(=O)O)[N+](=O)[O-]

InChI

InChI=1S/C7H5NO4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)

InChIKey

SLAMLWHELXOEJZ-UHFFFAOYSA-N

LogP

1.81620

pKa

2.16(at 18℃)

Complexity

198

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Stable. Incompatible with strong oxidizing agents, strong bases.

Sensitiveness

对湿度敏感

Synonyms & References

English

NSC-9576
2-Nitrobenzoic acid, 95%
N0155
552-16-9
nitro benzoic acid
ortho-nitrobenzoic acid
Oprea1_474365
NCGC00091364-01
2-Nitrobenzoic acid, technical, >=85% (HPLC)
CHEBI:25620
HY-Y0891
DTXSID5025738
NSC9576
CAS-552-16-9
Benzoic acid, 2-nitro-
2-Nitrobenzoic acid-ring-ul-14c
EN300-18349
S6S4653K7Z
2-Nitrobenzoic acid, 95%, Contains 3- and 4-isomers
o-Carboxynitrobenzene
NCGC00258573-01
EINECS 209-004-9
o-Nitrobenzoic acid
MFCD00007137
AC-652
D71183
CCRIS 2334
Benzoic acid, o-nitro-
NSC 9576
2-Nitrobenzoic acid, Vetec(TM) reagent grade, 94%
NS00022362

MDL Number

MFCD00007137

EC Number

209-004-9

Customs Code

29163900

FAQ

What is 2-Nitrobenzoic acid (CAS: 552-16-9)?

2-Nitrobenzoic acid (CAS: 552-16-9) is an organic compound with the chemical formula C7H5NO4. It is a white crystalline solid, known for its sharp odor, and exhibits acidic properties due to the carboxylic group. The molecule features a nitro group (-NO2) at the 2-position of the benzene ring, making it a key intermediate in various chemical syntheses. It is soluble in water and many organic solvents, with a melting point around 220°C.

What are the main uses of 2-Nitrobenzoic acid (CAS: 552-16-9)?

2-Nitrobenzoic acid (CAS: 552-16-9) is widely used in pharmaceuticals as an intermediate for drug development, including antihistamines and anti-inflammatory agents. It also serves in industrial applications such as dye manufacturing, pesticide production, and polymer synthesis. In research, it acts as a reagent for organic reactions and functional group modifications. Its versatility makes it valuable across chemical and material science fields.

Is 2-Nitrobenzoic acid (CAS: 552-16-9) safe?

2-Nitrobenzoic acid (CAS: 552-16-9) requires careful handling due to its potential toxicity. It is classified as a skin and respiratory irritant, and prolonged exposure may cause harm. Safety standards recommend using appropriate protective equipment, such as gloves and goggles, and working in a well-ventilated area. Proper disposal and adherence to OSHA guidelines are essential to ensure safe use and minimize health risks.

How should 2-Nitrobenzoic acid (CAS: 552-16-9) be stored?

2-Nitrobenzoic acid (CAS: 552-16-9) should be stored in a sealed, airtight container in a cool, dry place, away from light and moisture. It is stable under these conditions but may degrade if exposed to heat or humidity. Storage precautions include keeping it in a well-ventilated area and avoiding contact with incompatible materials to maintain its integrity and safety.