Linagliptin Impurity 67 (2-Aminoacetophenone)

Basic Information

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CAS Number

551-93-9

Molecular Formula

C8H9NO

Molecular Weight

135.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

20 ºC

Boiling Point

85-90 °C/0.5 mmHg

Refractive Index

n20/D 1.614(lit.)

SMILES

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CC(=O)c1ccccc1N

InChI

InChI=1S/C8H9NO/c1-6(10)7-4-2-3-5-8(7)9/h2-5H,9H2,1H3

InChIKey

GTDQGKWDWVUKTI-UHFFFAOYSA-N

LogP

1.4714

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

133

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

对空气敏感

Synonyms & References

English

1-(2-Aminophenyl)ethanone
1-(2-aminophenyl)-ethanone
2-AMINO-1-PHENYLETHANONE
2'-AMINOACETOPHENONE
2-AMINOACETOPHENONE
AMINOACETOPHENONE(2-)
ETHANONE, 1-(2-AMINOPHENYL)-
FEMA 3906
O-AMINOACETOPHENONE
O-AMINOPHENYL METHYL KETONE
1-(2-aminophenyl)-ethanon
1-Acetyl-2-aminobenzene
2’-amino-acetophenon
2-Acetylaniline
Acetophenone, 2'-amino-
o-acetylaniline
o-Aminoacetylbenzene
2'-AminoActophenone
ortho-aminoacetophenone
o-Aminoacetophenone
1-(2-Aminophenyl)-ethanone
2'-Aminoacetophenone

MDL Number

MFCD00007717

Customs Code

2914399090

FAQ

What is Linagliptin Impurity 67 (CAS: 551-93-9)?

Linagliptin Impurity 67, also known as 2-Aminoacetophenone (CAS: 551-93-9), is a chemical compound used primarily as an impurity in the drug Linagliptin. It has the molecular formula C8H11NO and is a white to yellowish solid with a mild aromatic odor. The compound is commonly found in pharmaceutical manufacturing processes and is important for quality control and purity assessment.

What are the main uses of Linagliptin Impurity 67 (CAS: 551-93-9)?

Linagliptin Impurity 67 (CAS: 551-93-9) is mainly used in the pharmaceutical industry as an impurity in the synthesis of Linagliptin, a DPP-4 inhibitors medication. It is also utilized in research settings for analytical purposes, such as impurity profiling and drug development. Additionally, it may be encountered in chemical synthesis and as a reference standard for testing.

Is Linagliptin Impurity 67 (CAS: 551-93-9) safe?

Linagliptin Impurity 67 (CAS: 551-93-9) is generally considered safe when handled properly, but it should be treated with standard chemical safety precautions. It is not classified as highly toxic, but it may cause skin or eye irritation upon contact. Safety data sheets (SDS) should be consulted for specific handling guidelines and protective measures to ensure safe use in laboratory and industrial settings.

How should Linagliptin Impurity 67 (CAS: 551-93-9) be stored?

Linagliptin Impurity 67 (CAS: 551-93-9) should be stored in a cool, dry place away from light. It is best kept in a tightly sealed container to prevent moisture absorption and contamination. Storage conditions should maintain a temperature below 25°C and humidity levels below 60% to ensure stability and prolong shelf life. Avoid exposure to strong oxidizing agents or incompatible substances.