Abemaciclib Impurity 4

Basic Information

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CAS Number

5509-65-9

Molecular Formula

C6H5F2N

Molecular Weight

129.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

144-148C

Boiling Point

154°C

Water Solubility

Slightly soluble in water.

Refractive Index

n20/D 1.508(lit.)

SMILES

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C1=CC(=C(C(=C1)F)N)F

InChI

InChI=1S/C6H5F2N/c7-4-2-1-3-5(8)6(4)9/h1-3H,9H2

InChIKey

ODUZJBKKYBQIBX-UHFFFAOYSA-N

LogP

1.547

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

87.1

Safety Information

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GHS Hazard Pictograms

H226

H302

H312

H317

H332

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H317 May cause an allergic skin reaction
Sensitization, Skin

H332 Harmful if inhaled
Acute toxicity, inhalation

Hazard Class

Class 3 Class 3

Synonyms & References

English

EINECS 226-853-0
NSC-127234
2,6-di-Fluoroaniline
Z104476070
UNII-943G3H8895
EN300-19913
5509-65-9
NSC 127234
2,6-difluorophenyl amine
D1635
Benzenamine, 2,6-difluoro-
DTXSID2073350
(2,6-difluorophenyl)amine
InChI=1/C6H5F2N/c7-4-2-1-3-5(8)6(4)9/h1-3H,9H
NSC127234
NS00043705
2,6-difluoro-aniline
CS-W020001
2,6-Difluoro-phenylamine
PS-9157
943G3H8895
2,6 difluoroaniline
W-105588
A19486
FT-0610644
MFCD00007655
2,6-DIFLUOROBENZENAMINE
AM20040700
2,6-difluoro aniline
F0001-1445
2,6-difluorobenzeneamine

MDL Number

MFCD00007655

Customs Code

2942000000

FAQ

What is Abemaciclib Impurity 4 (CAS: 5509-65-9)?

Abemaciclib Impurity 4 (CAS: 5509-65-9) is a chemical compound identified as a byproduct or contaminant during the synthesis of Abemaciclib. It is commonly used in pharmaceutical research for impurity analysis and quality control. The compound's exact chemical formula and molecular structure are not widely publicized, but it is characterized by its relevance in drug development processes and regulatory compliance testing.

What are the main uses of Abemaciclib Impurity 4 (CAS: 5509-65-9)?

Abemaciclib Impurity 4 (CAS: 5509-65-9) is primarily utilized in pharmaceutical research and quality assurance to identify and quantify impurities in Abemaciclib production. It plays a critical role in ensuring drug purity and safety standards. Additionally, it may be employed in analytical chemistry for method validation and in academic studies to understand synthetic pathways and compound behavior.

Is Abemaciclib Impurity 4 (CAS: 5509-65-9) safe?

Abemaciclib Impurity 4 (CAS: 5509-65-9) safety considerations are not extensively documented, but as a chemical impurity, it is typically handled with standard laboratory precautions. Users should avoid direct contact, inhalation, or ingestion, and wear appropriate personal protective equipment (PPE). Proper disposal and adherence to safety guidelines are essential, especially in pharmaceutical settings where exposure risks must be minimized.

How should Abemaciclib Impurity 4 (CAS: 5509-65-9) be stored?

Abemaciclib Impurity 4 (CAS: 5509-65-9) should be stored in a cool, dry place, away from direct light, in a sealed and airtight container. It is recommended to maintain storage conditions at 2-8°C to ensure stability. Avoid exposure to moisture and heat, and keep it in a controlled environment to prevent degradation or contamination.