4-Chloro-1H-pyrrolo[2,3-b]pyridine

Basic Information

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CAS Number

55052-28-3

Molecular Formula

C7H5ClN2

Molecular Weight

152.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

176-181 °C

Density

1.425 g/cm3??

Water Solubility

Slightly soluble in water.

Refractive Index

1.703

SMILES

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C1=CNC2=NC=CC(=C21)Cl

InChI

InChI=1S/C7H5ClN2/c8-6-2-4-10-7-5(6)1-3-9-7/h1-4H,(H,9,10)

InChIKey

HNTZVGMWXCFCTA-UHFFFAOYSA-N

LogP

2.2162999999999995

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

129

Safety Information

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GHS Hazard Pictograms

H301

H315

H318

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

W-203076
F2108-0145
4-chlor-1H-pyrrolo[2,3-b]pyridin
HNTZVGMWXCFCTA-UHFFFAOYSA-N
SCHEMBL100651
PB29499
CS-B0097
4-chloranyl-1H-pyrrolo[2,3-b]pyridine
BP-13250
4-chloro-1-H-pyrrolo[2,3-b]pyridine
A830464
CHEMBL4204893
AKOS004910656
FT-0642107
CS-W000189
4-Chloro-7-azaindole, 97%
4-choro-7-azaindole
N-(3-Chloro-2-methylpropyl)-N-methylformamide
4-chloro-1H-pyrrolo[2,3-b]pyridine
4Z-5015
4-Chloro-1H-pyrrolo[2,3-b]-pyridine
A7982
W-203973
SY004661
AM20061315
4-CHLORO-7-AZAINDOLE
AN-584/43416898
55052-28-3
EN300-99341
FT-0648837
AC-5049

MDL Number

MFCD08272232

Customs Code

2933990090

FAQ

What is 4-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 55052-28-3)?

4-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 55052-28-3) is a heterocyclic organic compound with the chemical formula C7H6ClN. It features a pyrrole ring fused to a pyridine ring, containing a chlorine atom at the 4th position. This compound is known for its aromatic properties and is commonly used in chemical synthesis. Its structure makes it a valuable intermediate in pharmaceutical and agrochemical research.

What are the main uses of 4-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 55052-28-3)?

4-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 55052-28-3) is primarily utilized in pharmaceutical research as a building block for developing drugs targeting neurological and metabolic disorders. It also finds applications in agrochemicals, materials science, and organic synthesis. Its unique chemical structure enables it to be a key component in the creation of various functional compounds, including ligands and intermediates for further derivatization.

Is 4-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 55052-28-3) safe?

4-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 55052-28-3) requires careful handling due to potential toxicity. It may cause skin and eye irritation, and inhalation should be avoided. Safety data sheets (SDS) recommend using protective gloves, goggles, and ensuring adequate ventilation. Proper disposal and adherence to safety standards are essential to minimize risks during handling and use.

How should 4-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 55052-28-3) be stored?

4-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 55052-28-3) should be stored in a tightly sealed container in a cool, dry place below 25°C. It is sensitive to moisture and light, so storage away from these elements is crucial. Maintain low humidity levels and ensure the container is made of inert material to preserve stability and prevent degradation.