6-Bromo-4-hydroxyquinolin-2(1H)-one

Basic Information

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CAS Number

54675-23-9

Molecular Formula

C9H6BrNO2

Molecular Weight

240.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

>300 ºC (ethanol )

Density

1.801±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=CC2=C(C=C1Br)C(=CC(=O)N2)O

InChI

InChI=1S/C9H6BrNO2/c10-5-1-2-7-6(3-5)8(12)4-9(13)11-7/h1-4H,(H2,11,12,13)

InChIKey

DQFPMEMMMGZBKU-UHFFFAOYSA-N

LogP

1.9961999999999995

Topological Polar Surface Area

53.089999999999996 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

264

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

6-Bromo-4-hydroxyquinolin-2(1H)-one
6-bromo-4-hydroxy-1H-quinolin-2-one
6-Bromo-4-hydroxy-2(1H)-quinolinone
6-Bromo-4-hydroxycarbostyril
6-Bromo-2-hydroxyquinolin-4(1H)-one
6-bromoquinoline-2,4-diol
2(1H)-Quinolinone, 6-bromo-4-hydroxy-
6-bromo-4-hydroxy-1,2-dihydroquinolin-2-one
6-Bromo-quinoline-2,4-diol
6-Bromo-2,4-quinolinediol
4-Hydroxy-6-brom-carbostyril
6-Bromo-2,4-dihydroxyquinoline
DQFPMEMMMGZBKU-UHFFFAOYSA-N
6-Bromo-4-hydroxy-1H-quinolin-2-one
SB71672
O11540
MFCD11847588
AKOS030623274
SCHEMBL2054683
CS-0041628
DA-04987
DB-169640
6-bromo-2-hydroxy-1H-quinolin-4-one
6-BROMO-4-HYDROXYQUINOLIN-2(1H)-ONE
2254506-51-7
6-Bromo-2-hydroxy-4(1h)-quinolinone
54675-23-9
6-bromo-4-hydroxycarbostyril
A870385
DS-1843
SY108412

MDL Number

MFCD11847588

FAQ

What are the physical and chemical properties of 6-Bromo-4-hydroxyquinolin-2(1H)-one (CAS: 54675-23-9)?

6-Bromo-4-hydroxyquinolin-2(1H)-one (CAS: 54675-23-9) is a crystalline solid with a molecular weight of approximately 267.03 g/mol. It has a melting point of 220-222°C and is slightly soluble in water. This compound shows moderate reactivity with bases and does not react with acids under normal conditions. It is stable under normal laboratory conditions but should be stored in a cool, dry place away from light.

How is 6-Bromo-4-hydroxyquinolin-2(1H)-one (CAS: 54675-23-9) typically synthesized?

6-Bromo-4-hydroxyquinolin-2(1H)-one (CAS: 54675-23-9) can be synthesized via a series of steps, including the bromination of 4-hydroxyquinolin-2(1H)-one followed by dehydration. This process typically involves the use of bromine in the presence of a suitable solvent. The reaction is carried out under mild conditions to achieve high selectivity and yield. Detailed procedures and conditions are outlined in various scientific literature.

What industries use 6-Bromo-4-hydroxyquinolin-2(1H)-one (CAS: 54675-23-9)?

6-Bromo-4-hydroxyquinolin-2(1H)-one (CAS: 54675-23-9) is primarily used in the pharmaceutical industry for the development of certain drugs. It also finds applications in the synthesis of functional materials, specifically in the production of sensors and semiconductors. Additionally, it is used in the formulation of some polymer-based materials due to its unique chemical properties.

What precautions should be taken when handling 6-Bromo-4-hydroxyquinolin-2(1H)-one (CAS: 54675-23-9)?

When handling 6-Bromo-4-hydroxyquinolin-2(1H)-one (CAS: 54675-23-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work must be conducted in a well-ventilated area or fume hood to avoid inhalation of potential fumes. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.