(Z)-N-(1-Hydroxyethylidene)glycine

Basic Information

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CAS Number

543-24-8

Molecular Formula

C4H7NO3

Molecular Weight

117.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

207-209 °C

Boiling Point

405.1℃ at 760 mmHg

Water Solubility

2.7 g/100 mL (15 ºC)

Flash Point

131.7±27.9 °C

Solubility

26.3g/l

Refractive Index

1.4540 (estimate)

Vapor Pressure

0.0±1.4 mmHg at 25°C

SMILES

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CC(=O)NCC(=O)O

InChI

InChI=1S/C4H7NO3/c1-3(6)5-2-4(7)8/h2H2,1H3,(H,5,6)(H,7,8)

InChIKey

OKJIRPAQVSHGFK-UHFFFAOYSA-N

LogP

-0.7929000000000002

pKa

3.669(at 25℃)

Topological Polar Surface Area

66.4 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

110

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

N-acetylglycine sodium salt
NS00015106
N-Acetylglycine, Vetec(TM) reagent grade, 98%
Glycine, N-acetyl-
acetyl-glycin
N-acetyl-glycine
acetamidoacetate
CH3CONHCH2COOH
FT-0629819
UNII-U2UT4677KR
InChI=1/C4H7NO3/c1-3(6)5-2-4(7)8/h2H2,1H3,(H,5,6)(H,7,8
Aceturic acid
AB00351
ACETYLAMINO-ACETIC ACID
AC-24104
AS-12785
N-acetyl glycine
aceturate
AM81782
A0093
EU-0096429
N-Acetylglycine, ReagentPlus(R), 99%
Acetylaminoacetic acid
s3098
Q15634040
SCHEMBL5876
Acetamidoacetic acid
2-acetamidoacetate
N-Acetylglycine Acetylglycine Acetamidoacetic acid
CHEMBL289004
AB00374931-02

MDL Number

MFCD00004275

Customs Code

29241900

FAQ

What is (Z)-N-(1-Hydroxyethylidene)glycine (CAS: 543-24-8)?

Z)-N-(1-Hydroxyethylidene)glycine (CAS: 543-24-8) is a chiral organic compound with the chemical formula C3H7NO3. It features a glycine backbone connected via a hydroxyethylidene bridge, exhibiting a Z configuration (cis isomer). This compound is known for its stability in aqueous solutions and is commonly used in chemical synthesis due to its reactivity and structural versatility. Its properties include solubility in water and a mild, characteristic odor.

What are the main uses of (Z)-N-(1-Hydroxyethylidene)glycine (CAS: 543-24-8)?

Z)-N-(1-Hydroxyethylidene)glycine (CAS: 543-24-8) is primarily used in pharmaceutical research as a chelating agent and in the synthesis of amino acid derivatives. It also finds applications in industrial processes for polymer development and as a precursor in the production of bioactive compounds. In the food industry, it may be utilized as a flavor enhancer, while in laboratory settings, it serves as a key intermediate for studying stereochemistry and reaction mechanisms.

Is (Z)-N-(1-Hydroxyethylidene)glycine (CAS: 543-24-8) safe?

Z)-N-(1-Hydroxyethylidene)glycine (CAS: 543-24-8) is generally considered safe when handled properly. However, it may cause mild skin or eye irritation upon contact. Safety data suggests it has low acute toxicity, but protective measures like gloves, safety goggles, and adequate ventilation are recommended. Compliance with OSHA and EPA guidelines ensures safe usage in controlled environments.

How should (Z)-N-(1-Hydroxyethylidene)glycine (CAS: 543-24-8) be stored?

Z)-N-(1-Hydroxyethylidene)glycine (CAS: 543-24-8) should be stored in a cool, dry place, away from direct light. Keep it in airtight, moisture-proof containers to maintain stability. It is typically stable under normal storage conditions but should be protected from high humidity and temperature fluctuations. Proper storage ensures longevity and prevents degradation or contamination.