1,10-Phenanthrolin-5-amine

Basic Information

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CAS Number

54258-41-2

Molecular Formula

C12H9N3

Molecular Weight

195.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

254-258 °C

Boiling Point

441.1℃ at 760 mmHg

Density

1.333

Flash Point

250.8±11.8 °C

Refractive Index

1.796

SMILES

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NC1=C2C=CC=NC2=C3N=CC=CC3=C1

InChI

InChI=1S/C12H9N3/c13-10-7-8-3-1-5-14-11(8)12-9(10)4-2-6-15-12/h1-7H,13H2

InChIKey

DKPSSMOJHLISJI-UHFFFAOYSA-N

LogP

2.3651999999999997

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

231

Safety Information

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GHS Hazard Pictograms

H302

H317

H318

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

H318 Causes serious eye damage
Serious eye damage/eye irritation

Synonyms & References

English

1,10-Phenanthrolin-5-amine
Amino-1,1,0-phenanthroline
5-AMINO-1,10-PHENANTHROLINE
1,10-Phenanthrolin-5-amine,(1,10)-Phenanthrolin-5-ylamine
1,10-Phenanthrolin-5
(1,10)PHENANTHROLIN-5-YLAMINE
DKPSSMOJHLISJI-UHFFFAOYSA-N
[1,10]Phenanthrolin-5-ylamine
CBDivE_011577
5-Amino-o-phenanthroline
NCDS-1
CBChromo1_000067
Oprea1_573308
1,10-Phenanthroline-5-amine
(1,10)-Phenanthrolin-5-ylamine

MDL Number

MFCD00455733

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1,10-Phenanthrolin-5-amine (CAS: 54258-41-2)?

1,10-Phenanthrolin-5-amine (CAS: 54258-41-2) is a crystalline solid with a molecular weight of approximately 166.19 g/mol. It has a solubility of about 1.4 g/100 mL in water. This compound is moderately reactive, particularly in acidic conditions, and can form stable complexes with various metal ions. It is commonly used in analytical chemistry and as a ligand in coordination chemistry.

How is 1,10-Phenanthrolin-5-amine (CAS: 54258-41-2) typically synthesized?

1,10-Phenanthrolin-5-amine is typically synthesized via the reduction of 1,10-phenanthroline with sodium borohydride or other suitable reducing agents. The reaction is usually carried out in aqueous solutions, and the product is isolated by filtration and recrystallization. This method provides good yield and selectivity, making it a common approach in laboratory practice.

What industries use 1,10-Phenanthrolin-5-amine (CAS: 54258-41-2)?

1,10-Phenanthrolin-5-amine (CAS: 54258-41-2) is widely used in the pharmaceutical industry for its chelating properties and in the development of metal-based drugs. It is also applied in the polymer industry for stabilizing polymer materials, in the sensor industry for metal ion detection, and in semiconductor manufacturing for etching processes.

What precautions should be taken when handling 1,10-Phenanthrolin-5-amine (CAS: 54258-41-2)?

When handling 1,10-Phenanthrolin-5-amine (CAS: 54258-41-2), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a closed container in a dry, well-ventilated area. In case of spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Safety data sheets (SDS) should be consulted for further handling and disposal information.