6-Chloro-5-methyl-3-pyridinol

Basic Information

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CAS Number

54232-03-0

Molecular Formula

C6H6ClNO

Molecular Weight

143.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

352.9℃ at 760 mmHg

Density

1.313±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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Oc1cnc(Cl)c(C)c1

InChI

InChI=1S/C6H6ClNO/c1-4-2-5(9)3-8-6(4)7/h2-3,9H,1H3

InChIKey

UGDSWVXJJFIVAH-UHFFFAOYSA-N

LogP

1.7490199999999998

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

99.1

Synonyms & References

English

3-Pyridinol, 6-chloro-5-methyl-
2-Bromo-5-hydroxy-3-methylpyridine
2-BROMO-5-HYDROXY-3-PICOLINE
2-Chloro-3-methyl-5-hydroxypyridine
2-CHLORO-5-HYDROXY-3-METHYL PYRDINE
2-Chloro-5-hydroxy-3-methylpyridine
2-Chloro-5-hydroxy-3-picoline
6-Chloro-5-methyl-pyridin-3-ol
6-Chloro-5-methylpyridin-3-ol
2-Chloro-5-Hydroxy-3-Methylpyrdine
6-CHLORO-5-METHYL-3-PYRIDINOL
PubChem12478
6-chloro-5-methylpyridine-3-ol
UGDSWVXJJFIVAH-UHFFFAOYSA-N
TRA0094053
PB31577
RP20873
SY024020
SC-0
6-chloro-5-methylpyridin-3-ol

MDL Number

MFCD11519295

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Chloro-5-methyl-3-pyridinol (CAS: 54232-03-0)?

6-Chloro-5-methyl-3-pyridinol (CAS: 54232-03-0) is a crystalline compound with a molecular weight of approximately 170.01 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions, and is stable under normal storage conditions.

How is 6-Chloro-5-methyl-3-pyridinol (CAS: 54232-03-0) typically synthesized?

6-Chloro-5-methyl-3-pyridinol (CAS: 54232-03-0) is typically synthesized through the reduction of 6-chloro-5-methyl-3-pyridone with a suitable reducing agent such as sodium borohydride. This method provides good selectivity and yield, with the reaction usually conducted in a basic aqueous solution.

What industries use 6-Chloro-5-methyl-3-pyridinol (CAS: 54232-03-0)?

6-Chloro-5-methyl-3-pyridinol (CAS: 54232-03-0) is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It also finds applications in the chemical industry, particularly in the development of sensors and polymers due to its unique chemical properties.

What precautions should be taken when handling 6-Chloro-5-methyl-3-pyridinol (CAS: 54232-03-0)?

When handling 6-Chloro-5-methyl-3-pyridinol (CAS: 54232-03-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place away from heat sources and oxidizing agents. In case of spillage, the area should be immediately ventilated and the spill cleaned up following standard safety procedures, and an SDS (Safety Data Sheet) should be consulted for detailed instructions.