5-Methoxy-2-pyrazinamine

Basic Information

View in Editor

CAS Number

54013-07-9

Molecular Formula

C5H7N3O

Molecular Weight

125.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

110-111 ºC

Boiling Point

258.7±35.0 ºC (760 Torr),

Density

1.224±0.06 g/cm3 (20 ºC 760 Torr),

Flash Point

110.3±25.9 ºC,

Refractive Index

1.567

SMILES

View in Editor

COC1=NC=C(N=C1)N

InChI

InChI=1S/C5H7N3O/c1-9-5-3-7-4(6)2-8-5/h2-3H,1H3,(H2,6,7)

InChIKey

BWXBZAOCBVXFMQ-UHFFFAOYSA-N

LogP

0.0673999999999999

Topological Polar Surface Area

61.03 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

88.3

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

MFCD09909647
SCHEMBL619998
54013-07-9
PB26534
2-amino-5-methoxy-pyrazine
DTXSID10561415
CS-W019181
BWXBZAOCBVXFMQ-UHFFFAOYSA-N
AC-7650
BB 0261492
AM20070361
EN300-105958
2-Pyrazinamine,5-methoxy-
pyrazinamine, 5-methoxy-
Q-103280
A7850
5-methoxypyrazin-2-amine
2-Amino-5-methoxypyrazine
SY017458
DS-10730
BCP23401
FT-0648991
AKOS005146149
5-methoxy-2-Pyrazinamine

MDL Number

MFCD09909647

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 5-Methoxy-2-pyrazinamine (CAS: 54013-07-9)?

5-Methoxy-2-pyrazinamine (CAS: 54013-07-9) is a crystalline solid with a molecular weight of approximately 158.14 g/mol. It is slightly soluble in water and ethanol. Reactively, it is stable under normal conditions but can undergo substitution reactions under certain conditions. The compound has a melting point of around 215-217°C.

How is 5-Methoxy-2-pyrazinamine (CAS: 54013-07-9) typically synthesized?

5-Methoxy-2-pyrazinamine can be synthesized through the aminomethylation of 2-pyrazinecarboxylic acid. Common methods include using methylamine in the presence of a catalyst such as sodium hydroxide. The reaction yields a high purity product with good selectivity and moderate to high yield.

What industries use 5-Methoxy-2-pyrazinamine (CAS: 54013-07-9)?

5-Methoxy-2-pyrazinamine (CAS: 54013-07-9) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the chemical industry for producing intermediates and additives. Additionally, it can be used in the polymer industry for special applications requiring unique chemical properties.

What precautions should be taken when handling 5-Methoxy-2-pyrazinamine (CAS: 54013-07-9)?

When handling 5-Methoxy-2-pyrazinamine (CAS: 54013-07-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood. Spills should be cleaned up immediately with appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.