N-Hydroxy-2-thiophenecarboximidamide

Basic Information

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CAS Number

53370-51-7

Molecular Formula

C5H6N2OS

Molecular Weight

142.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

90-96 °C

Boiling Point

258.7±32.0 ºC (760 Torr),

Density

1.45±0.1 g/cm3 (20 ºC 760 Torr),

Flash Point

110.3±25.1 ºC,

Refractive Index

1.675

SMILES

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C1=CSC(=C1)C(=NO)N

InChI

InChI=1S/C5H6N2OS/c6-5(7-8)4-2-1-3-9-4/h1-3,8H,(H2,6,7)

InChIKey

NKMNPRXPUZINOM-UHFFFAOYSA-N

LogP

0.8426

Topological Polar Surface Area

58.61 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

126

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

N'-hydroxythiophene-2-carboximidamide
HMS1780M14
108443-93-2
N-Hydroxythiophene-2-carboximidamide
Thiophene-2-amidoxime
MFCD00173698
53370-51-7
A829548
F2195-0002
AKOS025312289
1164246-20-1
Thiophene-2-amidoxime, 96%
n'-hydroxy-2-thiophenecarboximidamide
BB 0218105
N'-hydroxythiophene-2-carboxamidine
N-HYDROXY-THIOPHENE-2-CARBOXAMIDINE
4Z-0812
AKOS022185211
AKOS000366008
J-502663
EN300-34245
(Z)-N'-hydroxythiophene-2-carboximidamide
SCHEMBL1007641
2-Thiophenecarboximidamide,N-hydroxy-
N'-HYDROXY-2-THIOPHENECARBOXIMIDAMIDE
2-thiophenamidoxime
2-thiophene-amidoxime
2-Thiophenecarboximidamide,N-hydroxy
2-Thiophenecarboximidamide,N-hydroxy-(9CI)
N'-Hydroxy-2-thiophenecarbimide amide
N'-hydroxy-2-thiophenecarboximidamide (en)

MDL Number

MFCD00173698

Customs Code

2934999090

FAQ

What are the physical and chemical properties of N-Hydroxy-2-thiophenecarboximidamide (CAS: 53370-51-7)?

N-Hydroxy-2-thiophenecarboximidamide (CAS: 53370-51-7) is a white crystalline solid with a molecular weight of 195.22 g/mol. It has a high solubility in organic solvents like methanol and ethanol but is practically insoluble in water. Chemically, it is moderately reactive toward nucleophiles and can undergo substitution reactions.

How is N-Hydroxy-2-thiophenecarboximidamide (CAS: 53370-51-7) typically synthesized?

N-Hydroxy-2-thiophenecarboximidamide (CAS: 53370-51-7) is commonly synthesized via the condensation of 2-thiophenecarboxaldehyde with hydroxylamine hydrochloride in the presence of a suitable base. The reaction typically yields a mixture that can be purified by recrystallization from ethanol.

What industries use N-Hydroxy-2-thiophenecarboximidamide (CAS: 53370-51-7)?

N-Hydroxy-2-thiophenecarboximidamide (CAS: 53370-51-7) finds applications in the pharmaceutical industry for producing certain biologically active compounds. It is also used in the synthesis of polymers and as a precursor in sensor technology.

What precautions should be taken when handling N-Hydroxy-2-thiophenecarboximidamide (CAS: 53370-51-7)?

When handling N-Hydroxy-2-thiophenecarboximidamide (CAS: 53370-51-7), it is essential to use appropriate personal protective equipment (PPE), including gloves and goggles. Store in a well-ventilated area and avoid contact with moisture. In case of a spill, handle according to the Material Safety Data Sheet (MSDS) and use a fume hood for safety.