Indomethacin | CAS No. 53-86-1
Indomethacin
Basic Information
CAS Number
53-86-1
Molecular Formula
C19H16ClNO4
Molecular Weight
357.79 g/mol
Chemical Classification
Basic Physical Properties
Melting Point
155-162?°C
Boiling Point
499.4°C at 760 mmHg
Water Solubility
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Flash Point
255.8°C
Solubility
ethanol: 50 mg/mL, clear, yellow-green
Refractive Index
1.6800 (estimate)
Vapor Pressure
8.61E-11mmHg at 25°C
Safety Information
View Safety InformationGHS Hazard Pictograms
H300Hazard Statement
Acute toxicity, oral
Hazard Class
Toxicity
LD50 i.p. in rats: 13 mg/kg (Klaassen)
Synonyms & References
English
- Indomethacin
- indomethacin methanol solution
- indomethacin crystalline
- indomethacin usp
- indometacin
- 1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid
- INDOMETACIN POTASSIUM
- 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic Acid
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
- 吲哚美辛
- Indocin
- Indometacine
- Indomethacine
- Indocid
- Metindol
- Indomethazine
- Imbrilon
- Amuno
- Tannex
- Indomethacinum
- Mikametan
- Methazine
- Indoptol
- Confortid
- Artracin
- Inflazon
- Indomecol
- Metartril
- Infrocin
- Indoptic
MDL Number
MFCD00057095
Customs Code
2933290090
Related Compounds
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
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![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp)
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp)



![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure (3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp)
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp)




