1-(Chloromethyl)-2-isocyanatobenzene | CAS No. 52986-66-0
1-(Chloromethyl)-2-isocyanatobenzene
Basic Information
CAS Number
52986-66-0
Molecular Formula
C8H6ClNO
Molecular Weight
167.59 g/mol
AD
Basic Physical Properties
Boiling Point
45-47 °C/0.2 mmHg
Density
1.241 g/mL at 25 °C
Refractive Index
n20/D 1.567(lit.)
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H312
Harmful in contact with skin
Acute toxicity, dermal
Acute toxicity, dermal
H314
Causes severe skin burns and eye damage
Skin corrosion/irritation
Skin corrosion/irritation
H332
Harmful if inhaled
Acute toxicity, inhalation
Acute toxicity, inhalation
Hazard Class
Class 6.1
Class 6.1
Sensitiveness
Moisture Sensitive
Synonyms & References
English
- 2-(Chloromethyl)phenyl isocyanate
- FT-0608759
- W-200410
- 1-(chloromethyl)-2-isocyanatobenzene
- 52986-66-0
- SCHEMBL93414
- DTXSID30392708
- 2-(Chloromethyl)phenyl isocyanate, 98%
- 2-(Chloromethyl)phenylisocyanate
- GEO-00722
- MFCD00077427
- AKOS005257594
- 2-(chloromethyl)phenyl isocyanate
- (2-chloromethyl)phenyl isocyanate
- 1-chloromethyl-2-isocyanato-benzene
- 2-(3-METHOXY-PHENYL)-BENZOOXAZOL-5-YLAMINE
- o-chloromethylphenyl isocyanate
MDL Number
MFCD00077427
Customs Code
2929109000
FAQ
What regulatory guidelines apply to 1-(Chloromethyl)-2-isocyanatobenzene (CAS: 52986-66-0)?
1-(Chloromethyl)-2-isocyanatobenzene (CAS 52986-66-0) is subject to various regulatory guidelines, including GHS classification, which categorizes it as a flammable liquid and a skin and eye irritant. It is also regulated under REACH in the European Union, requiring registration for substances above 1 tonne annually. FDA and EPA regulations may apply for its use in pharmaceuticals and environmental applications, respectively, requiring proper handling, storage, and disposal to prevent environmental contamination and ensure worker safety.
Are there alternatives to 1-(Chloromethyl)-2-isocyanatobenzene (CAS: 52986-66-0) in synthesis?
There are several alternatives to 1-(Chloromethyl)-2-isocyanatobenzene (CAS 52986-66-0) in synthesis, including isomers such as 1-chloro-2-(isocyanatomethyl)benzene and 2-chloro-1-(isocyanatomethyl)benzene, as well as other isocyanate derivatives. Common alternative reagents include 1-(bromomethyl)-2-isocyanatobenzene and 1-(trifluoromethyl)-2-isocyanatobenzene, which can serve similar functional groups in various chemical reactions.
What is the market or research trend for 1-(Chloromethyl)-2-isocyanatobenzene (CAS: 52986-66-0)?
The market for 1-(Chloromethyl)-2-isocyanatobenzene (CAS 52986-66-0) is relatively niche, with increasing research trends in its use as a monomer for polymer synthesis and as a precursor in the production of pharmaceuticals and materials with specific functional groups. The demand is influenced by the development of new applications and the need for safer, more environmentally friendly alternatives to traditional isocyanates. Price trends are stable but may fluctuate based on supply chain disruptions and changes in regulatory landscape.
How should waste containing 1-(Chloromethyl)-2-isocyanatobenzene (CAS: 52986-66-0) be handled?
Waste containing 1-(Chloromethyl)-2-isocyanatobenzene (CAS 52986-66-0) should be managed carefully to prevent environmental contamination and ensure worker safety. Collection should be done in compatible containers, and the waste should be disposed of through incineration or professional waste disposal services that comply with local regulations. Environmental protection precautions include proper containment, neutralization of any acidic or basic components, and adherence to guidelines outlined by organizations such as the EPA and OSHA to minimize exposure risks and protect the environment.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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