4-[3-(4-Aminophenoxy)propoxy]aniline

Basic Information

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CAS Number

52980-20-8

Molecular Formula

C15H18N2O2

Molecular Weight

258.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

109-112 ºC

Density

1.177±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=CC(=CC=C1N)OCCCOC2=CC=C(C=C2)N

InChI

InChI=1S/C15H18N2O2/c16-12-2-6-14(7-3-12)18-10-1-11-19-15-8-4-13(17)5-9-15/h2-9H,1,10-11,16-17H2

InChIKey

KWFFEQXPFFDJER-UHFFFAOYSA-N

LogP

2.698900000000001

Topological Polar Surface Area

70.5 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

210

Synonyms & References

English

4,4'-(1,3-propanediyl)dioxydianiline
4-[3-(4-aminophenoxy)propoxy]aniline
1,3-Bis(4-aminophenoxy)propane
1,3-bis(4-aminophenyloxy)propane
1,3-bis(p-aminophenoxy)propane
1,3-propylene-bis(phenoxy-4-amine)
4,4'-[propane-1,3-diylbis(oxy)]dianiline
4-[3-(4-Aminophenoxy)propoxy]phenylamine
AC1LCAFO
AC1Q525I
CTK1G8198
SBB051752
SureCN561615
4,4'-[1,3-Propanediylbis(oxy)]bis[benzenamine]
4,4'-[1,3-Propanediyl]bis[oxy]-bis-benzeneamine
C15H18N2O2
A870851
DTXSID30341392
4-[3-(4-Aminophenoxy)propoxy]phenylamine #
4,4'-(Propane-1,3-diylbis(oxy))dianiline
Benzenamine, 4,4'-[1,3-propanediylbis(oxy)]bis-
CS-0453293
1,3-bis[4-aminophenoxy]propane
AKOS024319276
MFCD00025331
AS-62927
SCHEMBL561615
Benzenamine, 4-[3-(4-aminophenoxy)propoxy]-
52980-20-8

MDL Number

MFCD00025331

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 4-[3-(4-Aminophenoxy)propoxy]aniline (CAS: 52980-20-8)?

4-[3-(4-Aminophenoxy)propoxy]aniline (CAS: 52980-20-8) is a white crystalline solid with a molecular weight of approximately 319.39 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and dimethyl sulfoxide. This compound is known for its aromatic reactivity and good solubility in polar solvents. It is moderately reactive and can undergo various chemical transformations, such as substitution and condensation reactions.

How is 4-[3-(4-Aminophenoxy)propoxy]aniline (CAS: 52980-20-8) typically synthesized?

4-[3-(4-Aminophenoxy)propoxy]aniline (CAS: 52980-20-8) is typically synthesized through multi-step reactions involving the preparation of aniline, coupling with 4-aminophenol, and subsequent propoxylation. Commonly, the synthesis involves the use of an appropriate coupling agent and base to enhance reactivity. The yield and selectivity of the reaction can be optimized using specific catalysts and reaction conditions, ensuring a high-quality final product.

What industries use 4-[3-(4-Aminophenoxy)propoxy]aniline (CAS: 52980-20-8)?

4-[3-(4-Aminophenoxy)propoxy]aniline (CAS: 52980-20-8) finds applications in various industries, particularly in pharmaceuticals, where it can be used as a key intermediate for drug synthesis. It is also utilized in the production of dyes and pigments, and in the development of functional polymers and sensors. Additionally, this compound may be employed in the synthesis of electronic materials and semiconductors.

What precautions should be taken when handling 4-[3-(4-Aminophenoxy)propoxy]aniline (CAS: 52980-20-8)?

When handling 4-[3-(4-Aminophenoxy)propoxy]aniline (CAS: 52980-20-8), it is crucial to use appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be addressed using appropriate absorbents and the area should be cleaned thoroughly. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.