tetralin-1-ol

Basic Information

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CAS Number

529-33-9

Molecular Formula

C10H12O

Molecular Weight

148.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

28-32 °C

Boiling Point

102-104 °C/2 mmHg

Solubility

5.09g/l

Refractive Index

n20/D 1.564(lit.)

SMILES

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OC1CCCc2ccccc12

InChI

InChI=1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10-11H,3,5,7H2

InChIKey

JAAJQSRLGAYGKZ-UHFFFAOYSA-N

LogP

2.0563000000000002

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

133

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H316 Causes mild skin irritation
Skin corrosion/irritation

H320 Causes eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

1,2,3,4-Tetrahydronaphthalen-1-ol
alpha-Tetralol
1,2,3,4-Tetrahydro-1-naphthol
1,2,3,4-Tetrahydro-1-napthol
1-Naphthalenol, 1,2,3,4-tetrahydro-
ac-α-Tetralol
α-Tetralol
ac-Alpha-Tetralol
Tetralin-1-ol
1-Tetralol
1-Hydroxytetralin
.alpha.-Tetralol
Tetrahydro-1-naphthol (VAN)
Tetrahydro-1-naphthol
1-NAPHTHOL, 1,2,3,4-TETRAHYDRO-
1,2,3,4-Tetrahydro-alpha-naphthol
1,2,3,4-tetrahydronaphthol
JAAJQSRLGAYGKZ-UHFFFAOYSA-N
(-)-1,2,3,4-Tetrahydro-1-naphthol
1-hydroxytetraline
DSS
tetralin-1-ol

MDL Number

MFCD00001739

Customs Code

29062900

FAQ

What are the physical and chemical properties of tetralin-1-ol (CAS: 529-33-9)?

Tetralin-1-ol (CAS: 529-33-9) is a colorless to light yellow liquid with a molecular weight of approximately 128.18 g/mol. It has a pKa of around 14 and is slightly soluble in water but readily soluble in organic solvents. It is a reducing agent and can react with oxygen to form tetralin-1,2-diol.

How is tetralin-1-ol (CAS: 529-33-9) typically synthesized?

Tetralin-1-ol can be synthesized by reduction of tetralin with a suitable reducing agent such as sodium borohydride. Alternatively, it can be obtained as a by-product in the hydrogenation of phenylacetylene or by hydrogenolysis of tetralin. The reaction is typically carried out in an inert solvent like toluene at moderate temperature and pressure.

What industries use tetralin-1-ol (CAS: 529-33-9)?

Tetralin-1-ol (CAS: 529-33-9) is primarily used in the pharmaceutical industry for the synthesis of certain drugs, as a solvent in the preparation of polymers, and in the manufacturing of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling tetralin-1-ol (CAS: 529-33-9)?

When handling tetralin-1-ol (CAS: 529-33-9), ensure to wear appropriate personal protective equipment (PPE) such as safety goggles, gloves, and a lab coat. Work in a well-ventilated area or fume hood to prevent inhalation. Store it in a cool, dry place away from direct sunlight. In case of spillage, neutralize the solution with an appropriate base and dispose of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.