(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran | CAS No. 528-63-2

(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran

Basic Information

CAS Number

528-63-2

Molecular Formula

C22H28O5

Molecular Weight

372.46 g/mol

AD

Basic Physical Properties

Physical State

Powder

Melting Point

139-140 ºC (methanol )

CC1C(C(OC1C2=CC(=C(C=C2)OC)OC)C3=CC(=C(C=C3)OC)OC)C

InChI

InChI=1S/C22H28O5/c1-13-14(2)22(16-8-10-18(24-4)20(12-16)26-6)27-21(13)15-7-9-17(23-3)19(11-15)25-5/h7-14,21-22H,1-6H3/t13-,14+,21-,22+

InChIKey

JLJAVUZBHSLLJL-DQEHQXCCSA-N

LogP

4.805800000000005

Topological Polar Surface Area

46.150000000000006 Ų

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

418

Safety Information

View Safety Information

Storage Conditions

N/A

Synonyms & References

English

  • CHEMBL418309
  • 528-63-2
  • Galgravin
  • SCHEMBL4808653
  • HY-N5007
  • CHEBI:132648
  • DTXSID901318613
  • Furan, 2,4-bis(3,4-dimethoxyphenyl)tetrahydro-3,4-dimethyl-, (2alpha,3beta,4beta,5alpha)-
  • AKOS040760118
  • NCGC00160185-01
  • (2R,3R,4S,5S)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyl-tetrahydrofuran
  • BDBM50021519
  • (2R,3R,4S,5S)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyloxolane
  • (invertedexclamationmarkA)-Galgravin
  • (2S,3S,4R,5R)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyloxolane
  • rel-(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran
  • 2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrahydro-furan
  • CS-0032064
  • Furan,2,5-bis(3,4-dimethoxyphenyl)tetrahydro-3,4-dimethyl-, (2R,3R,4S,5S)-rel-
  • galgravin
  • (2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran
  • furan, 2,5-bis(3,4-dimethoxyphenyl)tetrahydro-3,4-dimethyl-, (2R,3R,4S,5S)-
  • (±)-Galgravin
  • Veraguensin
  • Galbelgin
  • Furan, 2,4-bis(3,4-dimethoxyphenyl)

MDL Number

MFCD30723086

FAQ

What is (2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran (CAS: 528-63-2)?

(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran is a chiral compound with a molecular formula of C18H22O4. It is a colorless liquid with a characteristic odor. This compound is characterized by its high purity and low volatility. It is commonly used in the pharmaceutical industry for the synthesis of chiral drugs and in organic synthesis as a chiral auxiliary.

What are the main uses of (2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran (CAS: 528-63-2)?

(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran is primarily used in the pharmaceutical industry for the synthesis of chiral drugs, due to its ability to act as a chiral auxiliary in organic synthesis. It is also used in the production of certain fine chemicals and as a reagent in organic reactions.

Is (2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran (CAS: 528-63-2) safe?

(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran is considered safe when handled according to standard laboratory safety protocols. However, it should be used with caution as it can cause skin irritation. Proper protective equipment, such as gloves and goggles, should be worn at all times. Inhalation of vapors should be avoided, and it should be stored in a well-ventilated area away from heat sources and direct sunlight.

How should (2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran (CAS: 528-63-2) be stored?

(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a sealed container to prevent evaporation and contamination. The storage area should be well-ventilated to avoid the buildup of toxic vapors. It is also important to keep it away from incompatible materials such as strong acids, bases, and oxidizers to ensure safety during storage and handling.

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