2-Thiophenecarboxylic acid

Basic Information

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CAS Number

527-72-0

Molecular Formula

C5H4O2S

Molecular Weight

128.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

125-127 °C

Boiling Point

260 °C

Water Solubility

80 g/L (20 ºC)

Flash Point

259-261℃

Refractive Index

1.5160 (estimate)

SMILES

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C1=CSC(=C1)C(=O)O

InChI

InChI=1S/C5H4O2S/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)

InChIKey

QERYCTSHXKAMIS-UHFFFAOYSA-N

LogP

1.4463

pKa

3.49(at 25℃)

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

103

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-thiophene-carboxylic acid
2-Thenoic acid
2-Thiophenecarboxylic acid, ReagentPlus(R), 99%
SCHEMBL83000
NSC2188
MFCD00005437
CHEBI:71241
2-thienoic acid
NCIOpen2_000991
C5H4O2S
AM20100294
2-Thienylcarboxylic acid
AI3-16118
thiophen-2-carboxylic acid
Tenoic acid (DCF)
AC-4922
T0218
Thenoic acid
A829248
2-thiophene carboxylic acid
2-Carboxythiophene
thiophencarboxylic acid
bmse000848
thiolcarboxylic acid
thienyl carboxylic acid
EN300-16724
NCGC00188253-01
BDBM50324678
alpha-Thiophenecarboxylic acid
thienoic acid
527-72-0

MDL Number

MFCD00005437

Customs Code

2934999090

FAQ

What is 2-Thiophenecarboxylic acid (CAS: 527-72-0)?

2-Thiophenecarboxylic acid (CAS: 527-72-0) is an organic compound containing a thiophene ring fused with a carboxylic acid group. It has the chemical formula C6H6O2S and is known for its aromatic structure and sulfur-containing functionality, which contribute to its reactivity and utility in chemical synthesis. It is commonly used as a building block in pharmaceutical and industrial applications due to its versatile chemical properties.

What are the main uses of 2-Thiophenecarboxylic acid (CAS: 527-72-0)?

2-Thiophenecarboxylic acid (CAS: 527-72-0) is widely used in pharmaceuticals for the synthesis of drugs and bioactive compounds. It also finds applications in the production of dyes, agrochemicals, and materials with specific functional properties. In research, it serves as an important intermediate in organic chemistry for developing new compounds and studying chemical reactivity.

Is 2-Thiophenecarboxylic acid (CAS: 527-72-0) safe?

2-Thiophenecarboxylic acid (CAS: 527-72-0) is generally considered safe when handled properly. However, it may cause skin and eye irritation, so protective measures such as gloves and safety goggles are recommended. Safety standards emphasize the importance of working in a well-ventilated area and following standard chemical handling protocols to minimize exposure and risk.

How should 2-Thiophenecarboxylic acid (CAS: 527-72-0) be stored?

2-Thiophenecarboxylic acid (CAS: 527-72-0) should be stored in a cool, dry, and well-ventilated place, away from light. It is typically kept in a sealed container to prevent moisture absorption and degradation. Storage conditions should ensure a stable environment to maintain its chemical integrity and prevent unwanted reactions.