(2R)-2-Amino-3-phenyl-1-propanol

Basic Information

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CAS Number

5267-64-1

Molecular Formula

C9H13NO

Molecular Weight

151.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

93-95 °C

Boiling Point

122°C/4mmHg

Flash Point

137.5℃

Solubility

Soluble in Dichloromethane, Ethyl Acetate, Methanol.

Refractive Index

23.5 ° (C=1.2, 1mol/L HCl)

Specific Rotation

23 º (c=1.2, 1 N HCl 22 ºC)

SMILES

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C1=CC=C(C=C1)CC(CO)N

InChI

InChI=1S/C9H13NO/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2/t9-/m1/s1

InChIKey

STVVMTBJNDTZBF-SECBINFHSA-N

LogP

0.5486999999999997

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

99.7

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

SOLRIAMFETOL METABOLITE M8
(R)-(+)2-amino-3-phenyl-1-propanol
Q27464374
D-phenyl alaninol
(2R)-2-amino-3-phenylpropan-1-ol
AS-12575
D-Phenylalaniol
D-Phenylalaninol
Benzenepropanol, .beta.-amino-, (R)-
P1289
DTXSID401316779
MFCD00064298
D(+)-Phenylalaninol;(R)-(+)-2-Amino-3-phenyl-1-propanol;D-Penylalaninol
CS-W018114
(r)(+)-2-amino-3-phenyl-1-propanol
2-Amino-3-phenyl-1-propanol #
F0001-2353
(2R)-3-PHENYL-2-AMINO-1-PROPANOL
A905772
(R)-2-Amino-3-phenyl-1-propanol
(2R)-2-amino-3-phenyl-1-propanol
(R)-(+)-PHENYLALANINOL
M04116
(R)-(+)-2-Amino-3-phenyl-1-propanol, 98%
AKOS000558103
Z1157651018
(+)-D-Phenylalaninol
(R)-1-hydroxymethyl-2-phenyl-ethylamine
HY-W017398
D-(+)-Phenylalaninol
BENZENEPROPANOL, .BETA.-AMINO-, (.BETA.R)-

MDL Number

MFCD00064298

Customs Code

2922199090

FAQ

What is (2R)-2-Amino-3-phenyl-1-propanol (CAS: 5267-64-1)?

(2R)-2-Amino-3-phenyl-1-propanol, with the CAS number 5267-64-1, is a chiral organic compound featuring an amino group, a hydroxyl group, and a phenyl ring. Its chemical formula is C9H13NO2, and it is known for its solubility in water and polar solvents. This compound is a key intermediate in pharmaceutical synthesis and is characterized by its role in modulating neurotransmitter activity due to its structural similarity to dopamine. Its stereochemistry (2R configuration) is critical for biological activity.

What are the main uses of (2R)-2-Amino-3-phenyl-1-propanol (CAS: 5267-64-1)?

(2R)-2-Amino-3-phenyl-1-propanol (CAS: 5267-64-1) is primarily used as a synthetic intermediate in pharmaceutical research, particularly in the development of antipsychotic drugs like risperidone. It also finds applications in the production of agrochemicals and as a tool compound for studying enzyme mechanisms. Due to its chemical structure, it is utilized in drug design to target specific receptors. Its versatility makes it valuable in both industrial and academic settings for creating complex molecules.

Is (2R)-2-Amino-3-phenyl-1-propanol (CAS: 5267-64-1) safe?

The safety of (2R)-2-Amino-3-phenyl-1-propanol (CAS: 5267-64-1) depends on exposure conditions. While it is generally considered safe in controlled environments, it may cause mild irritation to skin, eyes, or respiratory system upon contact. Proper handling requires protective equipment such as gloves and goggles. Safety data sheets (SDS) recommend avoiding inhalation of vapors and ensuring adequate ventilation. Adherence to OSHA and EPA guidelines is essential for safe use and disposal.

How should (2R)-2-Amino-3-phenyl-1-propanol (CAS: 5267-64-1) be stored?

(2R)-2-Amino-3-phenyl-1-propanol (CAS: 5267-64-1) should be stored in a cool, dry, and well-ventilated area, ideally below 25°C. It is sensitive to moisture and light, so storage in airtight, dark containers is recommended. To maintain stability, it should be kept away from strong oxidizers and incompatible chemicals. Refrigeration may be necessary for long-term storage, and protective measures should be taken to prevent contamination or degradation.