N-Methyl-L-tryptophan | CAS No. 526-31-8

Q: What are the physical and chemical properties of N-Methyl-L-tryptophan (CAS: 526-31-8)?

N-Methyl-L-tryptophan (CAS: 526-31-8) is a white crystalline powder with a molecular weight of 183.23 g/mol. It is sparingly soluble in water and ethanol, and insoluble in organic solvents like chloroform. This compound is primarily used in pharmaceutical and biochemical research. It exhibits moderate reactivity, particularly in amidation and reduction reactions.

Q: How is N-Methyl-L-tryptophan (CAS: 526-31-8) typically synthesized?

N-Methyl-L-tryptophan (CAS: 526-31-8) is synthesized from L-tryptophan via a simple N-methylation reaction using methyl iodide or methylamine under basic conditions. The reaction is typically performed at room temperature, and the yield is around 90%. This method is straightforward and efficient, making it a common choice for laboratory and industrial-scale production.

Q: What industries use N-Methyl-L-tryptophan (CAS: 526-31-8)?

N-Methyl-L-tryptophan (CAS: 526-31-8) is primarily used in the pharmaceutical and biochemical industries. It serves as a precursor for the synthesis of various tryptophan derivatives and is also utilized in the development of tryptophan-based drugs. Additionally, it has applications in research and development for studying tryptophan metabolism and its effects on the human body.

Q: What precautions should be taken when handling N-Methyl-L-tryptophan (CAS: 526-31-8)?

When handling N-Methyl-L-tryptophan (CAS: 526-31-8), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, neutralize the area with a basic solution, then clean up using absorbent material. Consult the Safety Data Sheet (SDS) for more detailed information on handling and disposal procedures.

N-Methyl-L-tryptophan

Basic Information

View in Editor

CAS Number

526-31-8

Molecular Formula

C12H14N2O2

Molecular Weight

218.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Cryst.

Melting Point

>300 °C (dec.)

Boiling Point

439.1±35.0°C at 760 mmHg

Flash Point

219.4 °C

Refractive Index

65 ° (C=1, 0.5mol/L NaOH)

Specific Rotation

+65 ° (c=1, 0.5M NaOH)

SMILES

View in Editor

O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC

InChI

InChI=1S/C12H14N2O2/c1-13-11(12(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,13-14H,6H2,1H3,(H,15,16)/t11-/m0/s1

InChIKey

CZCIKBSVHDNIDH-NSHDSACASA-N

LogP

1.383

Topological Polar Surface Area

65.11999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

257

Safety Information

View Safety Information

Hazard Statement

Storage Conditions

2-8℃

Synonyms & References

English

N-Methyl-L-tryptophan
ABRINE, L-(RG)
L-ABRINE
L-Tryptophan, N-methyl-
N-Me-Trp-OH
<small>L<
ABRINE
ABRINE,L
H-METRP-OH
L-N-Methyltryptophan
N(alpha)-methyl-L-tryptophan
N-methyl-tryptophan
N-ME-TRP-OH HCL
N-ME-TRYPTOPHAN
Nα-Methyl-L-tryptophan
N-Methyltryptophan
N-Methyl-L-tryptophane
L-(+)-Abrine
Nalpha-Methyl-L-tryptophan
P57TWL22IX
(2S)-3-(1H-indol-3-yl)-2-(methylamino)propanoic acid
CZCIKBSVHDNIDH-NSHDSACASA-N
(2S)-3-indol-3-yl-2-(methylamino)propanoic acid
(S)-3-(1H-Indol-3-yl)-2-(methylamino)propanoic acid
N-Metil-L-triptofano
methyl-l-tryptophan
N-methyl tryptophan
L
L-Abrine
N-α-Methyl-L-tryptophan
Tryptophan, N-methyl-, L- (6CI,7CI,8CI),N-Methyl-L-tryptophan,(S)-3-(1H-Indol-3-yl)-2-methylaminopro...

MDL Number

MFCD00467133

Customs Code

2933990090

FAQ

What are the physical and chemical properties of N-Methyl-L-tryptophan (CAS: 526-31-8)?

N-Methyl-L-tryptophan (CAS: 526-31-8) is a white crystalline powder with a molecular weight of 183.23 g/mol. It is sparingly soluble in water and ethanol, and insoluble in organic solvents like chloroform. This compound is primarily used in pharmaceutical and biochemical research. It exhibits moderate reactivity, particularly in amidation and reduction reactions.

How is N-Methyl-L-tryptophan (CAS: 526-31-8) typically synthesized?

N-Methyl-L-tryptophan (CAS: 526-31-8) is synthesized from L-tryptophan via a simple N-methylation reaction using methyl iodide or methylamine under basic conditions. The reaction is typically performed at room temperature, and the yield is around 90%. This method is straightforward and efficient, making it a common choice for laboratory and industrial-scale production.

What industries use N-Methyl-L-tryptophan (CAS: 526-31-8)?

N-Methyl-L-tryptophan (CAS: 526-31-8) is primarily used in the pharmaceutical and biochemical industries. It serves as a precursor for the synthesis of various tryptophan derivatives and is also utilized in the development of tryptophan-based drugs. Additionally, it has applications in research and development for studying tryptophan metabolism and its effects on the human body.

What precautions should be taken when handling N-Methyl-L-tryptophan (CAS: 526-31-8)?

When handling N-Methyl-L-tryptophan (CAS: 526-31-8), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, neutralize the area with a basic solution, then clean up using absorbent material. Consult the Safety Data Sheet (SDS) for more detailed information on handling and disposal procedures.