2-(Phenylthio)-5-(trifluoromethyl)benzonitrile | CAS No. 52548-95-5
2-(Phenylthio)-5-(trifluoromethyl)benzonitrile
Basic Information
CAS Number
52548-95-5
Molecular Formula
C14H8F3NS
Molecular Weight
279.28 g/mol
AD
Basic Physical Properties
Boiling Point
354°C at 760 mmHg
Density
1.35
Flash Point
167.9°C
Refractive Index
1.585
Safety Information
View Safety InformationHazard Statement
Hazard Class
Class TOXIC
Class TOXIC
Synonyms & References
English
- 2-cyano-4-(trifluoromethyl)diphenylsulfide
- 2-Cyano-4-(trifluoroMethyl)diphenylsulphide
- 2-Cyano-4-(trifluoromethyl)phenyl phenyl sulfide
- 2-(PHENYLTHIO)-5-(TRIFLUOROMETHYL)BENZONITRILE
- 2-phenylsulfanyl-5-(trifluoromethyl)benzonitrile
- AKOS005083014
- 2-Phenylsulfanyl-5-trifluoromethyl-benzonitrile
- 2-(phenylthio)-5-(trifluoromethyl)benzonitrile
- MFCD00069139
- DB-020971
- 1L-584S
- 2-Cyano-4-(trifluoromethyl)diphenylsulfide
- 2-(phenylthio)-5-trifluoromethyl-benzonitrile
- 2-(phenylsulfanyl)-5-(trifluoromethyl)benzonitrile
- 2-phenylsulfanyl-5-(trifluoromethyl)benzenecarbonitrile
- SCHEMBL11707664
- DTXSID80363408
- 2-Cyano-4-(trifluoromethyl)diphenylsulphide
- 52548-95-5
- CS-0327071
- A829140
MDL Number
MFCD00069139
Customs Code
2930909090
FAQ
What are the physical and chemical properties of 2-(Phenylthio)-5-(trifluoromethyl)benzonitrile (CAS: 52548-95-5)?
2-(Phenylthio)-5-(trifluoromethyl)benzonitrile is a crystalline solid with a molecular weight of approximately 319.04 g/mol. It has limited water solubility and good solubility in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with strong nucleophiles. It is used in the synthesis of functional materials and pharmaceuticals.
How is 2-(Phenylthio)-5-(trifluoromethyl)benzonitrile (CAS: 52548-95-5) typically synthesized?
2-(Phenylthio)-5-(trifluoromethyl)benzonitrile is synthesized via a multi-step process, usually involving the nucleophilic substitution of a trifluoromethylated benzyl halide with phenyl thiol. Commonly, this is achieved using a palladium-catalyzed cross-coupling reaction. The yield and selectivity are generally high, depending on the reaction conditions.
What industries use 2-(Phenylthio)-5-(trifluoromethyl)benzonitrile (CAS: 52548-95-5)?
2-(Phenylthio)-5-(trifluoromethyl)benzonitrile is used in the pharmaceutical and polymer industries for the development of specialized compounds and materials. It also finds applications in the production of sensors and semiconductors due to its specific functional groups.
What precautions should be taken when handling 2-(Phenylthio)-5-(trifluoromethyl)benzonitrile (CAS: 52548-95-5)?
When handling 2-(Phenylthio)-5-(trifluoromethyl)benzonitrile, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and ignition sources. Spills should be handled with care, and the material safety data sheet (MSDS) should be consulted for detailed instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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