L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine | CAS No. 52498-25-6

L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine

Basic Information

CAS Number

52498-25-6

Molecular Formula

C43H68N12O9

Molecular Weight

897.09 g/mol

AD

Basic Physical Properties

CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(C(C)CC)C(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)N

InChI

InChI=1S/C43H68N12O9/c1-7-24(5)34(40(61)51-31(20-27-21-47-22-49-27)41(62)55-18-10-12-32(55)38(59)54-35(42(63)64)25(6)8-2)53-37(58)30(19-26-13-15-28(56)16-14-26)50-39(60)33(23(3)4)52-36(57)29(44)11-9-17-48-43(45)46/h13-16,21-25,29-35,56H,7-12,17-20,44H2,1-6H3,(H,47,49)(H,50,60)(H,51,61)(H,52,57)(H,53,58)(H,54,59)(H,63,64)(H4,45,46,48)/t24-,25-,29-,30-,31-,32-,33-,34-,35-/m0/s1

InChIKey

MOLXDYACMRLMMF-GIBVOHFOSA-N

LogP

-0.261129999999996

Topological Polar Surface Area

339.93999999999994 Ų

Hydrogen Bond Donor/Acceptor

14 / 21

Complexity

1610

Synonyms & References

English

  • 52498-25-6
  • (2S,3S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoic acid
  • Angiotensin III, isoleucine(7)-
  • 7-Isoleucine-aiii
  • Angiotensin III, ile(7)-
  • [Ile7] angiotensin iii
  • Angiotensin III inhibitor (human)
  • (2S,3S)-2-((S)-1-((6S,9S,12S,15S,18S)-18-((1H-imidazol-4-yl)methyl)-1,6-diamino-15-sec-butyl-12-(4-hydroxybenzyl)-1-imino-9-isopropyl-7,10,13,16-tetraoxo-2,8,11,14,17-pentaazanonadecane)pyrrolidine-2-carboxamido)-3-methylpentanoic acid
  • Argininyl-valinyl-tyrosinyl-isoleucinyl-histidinyl-prolinyl-isoleucine
  • CHEMBL2371409
  • 7-Ile-angiotensin III
  • Aiii, ile(7)-
  • Angiotensin IIIinhibitor (human) (9CI)
  • (Des-Asp1,Ile8)-Angiotensin II
  • L-ARG-VAL-TYR-ILE-HIS-PRO-ILE
  • [Ile7]-angiotensin III
  • ANGIOTENSIN III
  • angiotensin III,Ile(7)
  • ARG-VAL-TYR-ILE-HIS-PRO-ILE
  • Des-Asp1-[Ile8]-Angiotensin II

MDL Number

MFCD00167456

FAQ

What is L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine (CAS: 52498-25-6)?

L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine (CAS: 52498-25-6) is a synthetic pentapeptide derived from specific amino acids. It is a complex structure with unique biological activities, making it suitable for various applications in research and pharmaceuticals.

What are the main uses of L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine (CAS: 52498-25-6)?

L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine (CAS: 52498-25-6) is primarily used in research for protein and peptide studies, and in pharmaceutical applications for its potential therapeutic benefits. It may also serve as a component in biological assays and formulations.

Is L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine (CAS: 52498-25-6) safe?

L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine (CAS: 52498-25-6) is generally safe when handled properly. However, it is important to follow safety guidelines, including wearing appropriate personal protective equipment, to prevent skin contact and inhalation. Storage should be secure to prevent accidental exposure.

How should L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine (CAS: 52498-25-6) be stored?

L-Arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine (CAS: 52498-25-6) should be stored in a cool, dry place, protected from light and moisture. It is recommended to keep the compound in a tightly sealed container to maintain its stability and potency. Avoid exposure to high temperatures and direct sunlight.

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