5-Chloro-1H-imidazo[4,5-b]pyridine

Basic Information

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CAS Number

52090-89-8

Molecular Formula

C6H4ClN3

Molecular Weight

153.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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Clc1ccc2nc[nH]c2n1

InChI

InChI=1S/C6H4ClN3/c7-5-2-1-4-6(10-5)9-3-8-4/h1-3H,(H,8,9,10)

InChIKey

UWUBPQVLQOHMKF-UHFFFAOYSA-N

LogP

1.6112999999999993

Topological Polar Surface Area

41.57 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Synonyms & References

English

5-Chloro-3H-imidazo[4,5-b]pyridine
3H-Imidazo[4,5-b]pyridine, 5-chloro-
5-chloro-1H-imidazo[4,5-b]pyridine
5-chloro-3H-imidazo[4,5-b]pyridine

MDL Number

MFCD01646134

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 5-Chloro-1H-imidazo[4,5-b]pyridine (CAS: 52090-89-8)?

5-Chloro-1H-imidazo[4,5-b]pyridine (CAS: 52090-89-8) should comply with the GHS classification, which categorizes it as a skin irritant and eye irritant. Additionally, it must adhere to REACH regulations in the EU, ensuring that its production, import, and use are documented and reported. In the USA, FDA and EPA regulations also apply, focusing on the safe handling, storage, and disposal of this compound to prevent environmental contamination.

Are there alternatives to 5-Chloro-1H-imidazo[4,5-b]pyridine (CAS: 52090-89-8) in synthesis?

Yes, there are alternative compounds that can serve similar functions in synthesis. For example, 4-Chloro-1H-imidazole and 1-Methyl-1H-imidazo[4,5-b]pyridine are common analogs. In terms of reagents, alternatives such as 2-Chloro-3-(imidazol-1-yl)pyridine can be used as less toxic substitutes. These alternatives are often chosen based on the specific requirements of the reaction and the desired product properties.

What is the market or research trend for 5-Chloro-1H-imidazo[4,5-b]pyridine (CAS: 52090-89-8)?

The market for 5-Chloro-1H-imidazo[4,5-b]pyridine (CAS: 52090-89-8) is growing due to its applications in pharmaceutical research, particularly as an intermediate in drug synthesis. Research trends indicate an increasing focus on its use in developing antifungal and antiparasitic agents. Additionally, there is a rising interest in studying its potential as a herbicide component. Market dynamics show a positive demand for this compound, driven by its unique chemical properties and emerging applications.

How should waste containing 5-Chloro-1H-imidazo[4,5-b]pyridine (CAS: 52090-89-8) be handled?

Waste containing 5-Chloro-1H-imidazo[4,5-b]pyridine (CAS: 52090-89-8) should be collected in appropriate containers and labeled with the correct hazardous waste symbol. The waste should be stored in a secure, ventilated area away from ignition sources. For disposal, it is recommended to use professional waste disposal services that specialize in hazardous chemicals. Proper incineration or chemical neutralization methods should be employed to ensure the compound is handled safely and environmentally responsibly, minimizing the risk of contamination and ensuring compliance with local and international regulations.