(6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione

Basic Information

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CAS Number

520-85-4

Molecular Formula

C22H32O3

Molecular Weight

344.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

215.0 to 220.0 deg-C

Boiling Point

496.4°C at 760 mmHg

Flash Point

263°C

Refractive Index

1.5000 (estimate)

Specific Rotation

D25 +75° (in chloroform)

SMILES

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CC1CC2C(CCC3(C2CCC3(C(=O)C)O)C)C4(C1=CC(=O)CC4)C

InChI

InChI=1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1

InChIKey

FRQMUZJSZHZSGN-HBNHAYAOSA-N

LogP

4.084400000000003

Topological Polar Surface Area

54.37 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

664

Safety Information

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GHS Hazard Pictograms

H361

Hazard Statement

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

Pregn-4-ene-3,20-dione, 17-hydroxy-6-alpha-methyl-
Medroxyprogesteronum
AKOS015961681
6.alpha.-Methyl-17.alpha.-hydroxyprogesterone
NCGC00023064-04
Farlutal inyectable
17.alpha.-Hydroxy-6.alpha.-methylprogesterone
(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
M3113
DTXCID8016508
17alpha-Hydroxy-6alpha-methylprogesterone;U8840
Medrossiprogesterone [DCIT]
MEDROXYPROGESTERONE ACETATE IMPURITY B [WHO-IP]
MEDROXYPROGESTERONE [MI]
Medroxyprogesteron
17-Hydroxy-6alpha-methylprogesterone
MLS000069571
SMR000058769
MEDROXYPROGESTERONE [WHO-DD]
17-Hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione
HY-B0648
U 8840
17-Hydroxy-6-methylprogesterone;U8840
Medroxyprogesteronum (INN-Latin)
6-alpha-Methyl-17-alpha-hydroxyprogesterone
MEDROXYPROGESTERONE [INN]
Medroxiprogesteronum
NSC 27408
CS-0694930
Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6-alpha)-
NSC27408

MDL Number

MFCD00069474

Customs Code

29372390

FAQ

What regulatory guidelines apply to (6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione (CAS: 520-85-4)?

The compound (6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione (CAS: 520-85-4) is subject to various regulatory guidelines. In terms of the Globally Harmonized System (GHS), it may fall under specific categories based on its physical and health hazards. Additionally, it is regulated under the REACH (Registration, Evaluation, Authorization, and Restriction of Chemicals) framework in the European Union. In the United States, the FDA (Food and Drug Administration) and EPA (Environmental Protection Agency) may also have specific requirements related to its use, handling, and disposal. Compliance with these guidelines is essential to ensure safety and legality.

Are there alternatives to (6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione in synthesis?

Alternatives to (6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione (CAS: 520-85-4) in synthesis include other progesterone derivatives and analogs such as hydroxyprogesterone or other 6-methylpregnenolones. These alternatives can offer similar biological activities or different properties depending on the specific application. Researchers often explore these options for their reactivity, solubility, and potential for specific therapeutic indications.

What is the market or research trend for (6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione (CAS: 520-85-4)?

The market and research trends for (6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione (CAS: 520-85-4) are focused on its use in hormone therapy and contraceptive development. There is ongoing research into its potential as a progestin, particularly in gynecological applications. Market trends suggest increasing interest in its synthetic modifications and its role in reproductive health, though specific trends can vary based on regional regulations and clinical needs.

How should waste containing (6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione (CAS: 520-85-4) be handled?

Waste containing (6alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione (CAS: 520-85-4) should be handled according to the local waste management regulations and the guidelines provided by the chemical supplier. Typically, this involves proper collection in sealed containers, minimization of spillage, and safe transportation to a professional waste disposal facility. Environmental protection measures should include the use of appropriate personal protective equipment (PPE) and adherence to safety protocols to prevent contamination and ensure the safety of the handlers and the environment.