5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril | CAS No. 51781-14-7

5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril

Basic Information

CAS Number

51781-14-7

Molecular Formula

C12H13NO3

Molecular Weight

219.24 g/mol

AD

Basic Physical Properties

C1CC(=O)NC2=C1C(=CC=C2)OCC3CO3

InChI

InChI=1S/C12H13NO3/c14-12-5-4-9-10(13-12)2-1-3-11(9)16-7-8-6-15-8/h1-3,8H,4-7H2,(H,13,14)

InChIKey

VQTWQOBNPISQPG-UHFFFAOYSA-N

LogP

1.3489

Topological Polar Surface Area

50.86 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

281

Synonyms & References

English

  • 5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril
  • 5-((OXIRAN-2-YL)METHOXY)-3,4-DIHYDROQUINOLIN-2(1H)-ONE
  • 5-(oxiran-2-ylmethoxy)-3,4-dihydro-1H-quinolin-2-one
  • 2(1H)-Quinolinone,3,4-dihydro-5-(oxiranylmethoxy)
  • 3,4-Dihydro-5-(2-oxiranylmethoxy)-2(1H)-quinolinone
  • 5-(oxiran-2-ylmethoxy)-3,4-dihydroquinolin-2(1H)-one
  • 5-(2,3-epoxypropoxy)-3,4-dihydro-2-quinolinone
  • 2(1H)-Quinolinone, 3,4-dihydro-5-(2-oxiranylmethoxy)-
  • 1-(3,4-dihydrocarbostyril-5-yloxy) -2,3-epoxypropane
  • 5-[(oxiran-2-yl)methoxy]-1,2,3,4-tetrahydroquinolin-2-one
  • 5-(OXIRAN-2-YLMETHOXY)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE
  • 2WA9ZP4G9Y
  • 5-[(Oxiran-2-yl)methoxy]-3,4-dihydroquinolin-2(1H)-one
  • 5-(((2RS)-Oxiran-2-yl)methoxy)-3,4-dihydroquinolin-2(1H)-one
  • DTXSID30512545
  • 5-(Oxiran-2-ylmethoxy)-3,4-dihydroquinolin-2(1H)-one
  • 1-(3,4-dihydro-2-hydroxy-quinolin-5-yloxy)-2,3-epoxypropane
  • 1-(3,4-dihydrocarbostyril-5-yloxy)-2,3-epoxypropane
  • starbld0049131
  • EN300-10843697
  • VQTWQOBNPISQPG-UHFFFAOYSA-N
  • CARTEOLOL HYDROCHLORIDE IMPURITY C [EP IMPURITY]
  • UNII-2WA9ZP4G9Y
  • 51781-14-7
  • SCHEMBL4902708
  • Carteolol hydrochloride impurity C [EP]
  • SCHEMBL8052757
  • 5-(2,3-epoxy-propoxy)-3,4-dihydro-carbostyril
  • DB-263288

FAQ

What are the physical and chemical properties of 5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril (CAS: 51781-14-7)?

5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril is a crystalline solid with a molecular weight of approximately 316.34 g/mol. It has a limited solubility in water but is more soluble in organic solvents like dichloromethane and methanol. Chemically, it is highly reactive, particularly towards epoxide ring opening and nucleophilic substitution reactions.

How is 5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril (CAS: 51781-14-7) typically synthesized?

5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril is synthesized via epoxidation of the corresponding alcohol followed by ring closure. Commonly, this involves treatment of the alcohol with peroxyacids or peroxyesters as the epoxidation agent. The reaction is performed under mild conditions, and the product is isolated through column chromatography.

What industries use 5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril (CAS: 51781-14-7)?

5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril is primarily used in pharmaceuticals for its reactive epoxide group, which can be functionalized to create new drug molecules. It also finds applications in the polymer industry for its ability to enhance polymer properties and in the semiconductor industry due to its structural features.

What precautions should be taken when handling 5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril (CAS: 51781-14-7)?

When handling 5-(2,3-Epoxypropoxy)-3,4-dihydrocarbostyril, it is essential to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and safety goggles. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, it is crucial to clean up immediately and consult the safety data sheet (SDS) for specific cleanup procedures.

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