(2R)-2-(Chloromethyl)oxirane

Basic Information

View in Editor

CAS Number

51594-55-9

Molecular Formula

C3H5ClO

Molecular Weight

92.53 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Melting Point

-48°C

Boiling Point

116°C

Refractive Index

n20/D 1.438(lit.)

Vapor Pressure

10 mmHg ( 16.6 °C)

Specific Rotation

34 º (589nm, c=1, MeOH)

SMILES

View in Editor

C1C(O1)CCl

InChI

InChI=1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2/t3-/m0/s1

InChIKey

BRLQWZUYTZBJKN-VKHMYHEASA-N

LogP

0.624

Topological Polar Surface Area

12.53 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

37.9

Safety Information

View Safety Information

GHS Hazard Pictograms

H226

H301

H311

H314

H317

H331

H350

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H301 Toxic if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H331 Toxic if inhaled
Acute toxicity, inhalation

H350 May cause cancer
Carcinogenicity

Hazard Class

Class 6.1 (3) Class 6.1 (3)

Explosive Limit

21%

Synonyms & References

English

CS-0005957
R-epi-chlorohydrin
(R)-1-Chloro-2,3-epoxypropane
Q26840862
(r)-(-)-epiclorohydrin
(2R)-2-(chloromethyl)oxirane
R-(-)-Epichlorohydrin
5-17-01-00020 (Beilstein Handbook Reference)
(R)-(-)-2-(Chloromethyl)oxirane
DTXSID501014417
BCP08874
MFCD00077759
(R)-Epichlorohydrin
Oxirane, 2-(chloromethyl)-, (2R)-
A828677
(R,S)-2-Chloromethyl-oxirane
(R)(-)epichlorohydrin
(R)-(-)epichlorhydrine
(R)-2-(chloromethyl) oxirane
Epichlorohydrin, (-)-
CHEBI:18662
(2R)-(-)-3-Chloro-1,2-propenoxide
2-(Chloromethyl)oxirane #
(R)-(-)-epichlorhydrine
r-epichlorohydrine
(R)-(-)Epichlorhydrin
(-)-Epichlorohydrin
(R)-(-)-Epichlorohydrin
VEC01H609I
(R)-epi-chlorohydrin
E0581

MDL Number

MFCD00077759

FAQ

What is (2R)-2-(Chloromethyl)oxirane (CAS: 51594-55-9)?

(2R)-2-(Chloromethyl)oxirane, with the CAS number 51594-55-9, is a reactive organic compound featuring a three-membered epoxide ring and a chloromethyl group attached to the second carbon. Its chemical formula is C3H5ClO, and it is commonly used as an intermediate in chemical synthesis. The compound is a colorless liquid with a pungent odor and exhibits flammability due to its volatile nature.

What are the main uses of (2R)-2-(Chloromethyl)oxirane (CAS: 51594-55-9)?

(2R)-2-(Chloromethyl)oxirane (CAS: 51594-55-9) is widely utilized in pharmaceuticals for synthesizing bioactive compounds and in industrial applications such as polymer production. It also serves as a key reagent in organic chemistry research, particularly in the development of new materials and functionalized chemicals. Its versatility makes it relevant in drug discovery and chemical manufacturing processes.

Is (2R)-2-(Chloromethyl)oxirane (CAS: 51594-55-9) safe?

Safety of (2R)-2-(Chloromethyl)oxirane (CAS: 51594-55-9) depends on proper handling. It is classified as a hazardous chemical due to its potential to cause skin and eye irritation, as well as respiratory harm upon inhalation. Precautions include using personal protective equipment (PPE), ensuring adequate ventilation, and following safety data sheet (SDS) guidelines to minimize exposure and health risks.

How should (2R)-2-(Chloromethyl)oxirane (CAS: 51594-55-9) be stored?

(2R)-2-(Chloromethyl)oxirane (CAS: 51594-55-9) should be stored in a sealed, cool, and dry container, away from light and incompatible materials. It is stable at room temperature (below 25°C) but may degrade if exposed to moisture or extreme temperatures. Storage in glass containers is recommended to prevent reaction with plastic, and it should be kept in a well-ventilated area to ensure safety.