Cimetidine | CAS No. 51481-61-9

Cimetidine

Basic Information

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CAS Number

51481-61-9

Molecular Formula

C10H16N6S

Molecular Weight

252.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

141.0 to 143.0 deg-C

Boiling Point

476.2±55.0 °C at 760 mmHg

Water Solubility

0.5 g/100 mL at 20 ºC

Flash Point

241.8±31.5 °C

Refractive Index

1.5700 (estimate)

SMILES

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CNC(=NC#N)NCCSCc1nc[nH]c1C

InChI

1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)

InChIKey

AQIXAKUUQRKLND-UHFFFAOYSA-N

LogP

1.37918

Complexity

296

Safety Information

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GHS Hazard Pictograms

H360

Hazard Statement

H360 May damage fertility or the unborn child
Reproductive toxicity

Toxicity

LD50 in mice, rats (mg/kg): 2600, 5000 orally; 150, 106 i.v.; 470, 650 i.p. (Brimblecombe)

Synonyms & References

English

N-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
ALTRAMET
CIMETIDINE
CIMETIDINE A
CIMETIDINE A TYPE
CIMITIDINE
N-CYANO-N'-METHYL-N''-[[2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]THIO]ETHYL]GUANIDINE
SKF-92334
TAGAMET
Acibilin
Acinil
Cimal
Cimetag
Cimetum
Dyspamet
Edalene
Eureceptor
FPF 1002
1-CYANO-2-METHYL-3-(2-(((5-METHYL-4-IMIDAZOLYL)METHYL)THIO)ETHYL)GUANIDINE
Cimetidine (free base)
2-Cyano-1-methyl-3-[2-(5-methyl-1H-imidazol-4-yl-methylthio)ethyl]guanidine
2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine
Tametin
Ulcedine
Ulcedin
Tratul
Gastromet
Cimetidina
Ulcomet
Ulcimet
Ulhys

MDL Number

MFCD00133296

Customs Code

2933990090

FAQ

What is Cimetidine (CAS: 51481-61-9)?

Cimetidine is a histamine H2-receptor antagonist with the chemical formula C12H13N5S. It works by reducing stomach acid production and is commonly used as a medication. Cimetidine is a white to off-white powder, slightly soluble in water, and has a molecular weight of 267.3 g/mol. Its CAS number is 51481-61-9, ensuring accurate identification in scientific contexts.

What are the main uses of Cimetidine (CAS: 51481-61-9)?

Cimetidine is primarily used to treat gastrointestinal conditions like peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. It inhibits acid secretion by blocking H2 receptors in the stomach lining. Additionally, it may be used off-label for other purposes, such as managing certain skin conditions or as a research tool. Its CAS number is 51481-61-9, making it a key compound in pharmaceutical applications.

Is Cimetidine (CAS: 51481-61-9) safe?

Cimetidine is generally safe when used as directed, but it may cause side effects like drowsiness, headache, or diarrhea. Precautions include avoiding use in children and pregnant women unless prescribed. Proper handling and disposal are essential to prevent environmental contamination. Safety standards emphasize adherence to medical guidelines and manufacturer instructions for its CAS 51481-61-9 formulation.

How should Cimetidine (CAS: 51481-61-9) be stored?

Cimetidine should be stored in a cool, dry place (15-30°C) away from moisture and light. Keep it in a tightly sealed container to maintain stability. Avoid exposure to heat and direct sunlight. Proper storage conditions for CAS 51481-61-9 ensure longevity and effectiveness, preventing degradation or contamination.