(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-hydroxyphenyl)propanoic acid | CAS No. 511272-35-8

(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-hydroxyphenyl)propanoic acid

Basic Information

CAS Number

511272-35-8

Molecular Formula

C24H21NO5

Molecular Weight

403.43 g/mol

AD

Basic Physical Properties

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC(=O)O)C4=CC(=CC=C4)O

InChI

InChI=1S/C24H21NO5/c26-16-7-5-6-15(12-16)22(13-23(27)28)25-24(29)30-14-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-12,21-22,26H,13-14H2,(H,25,29)(H,27,28)/t22-/m1/s1

InChIKey

LZJDAHKCUYUTCN-JOCHJYFZSA-N

LogP

4.446700000000003

Topological Polar Surface Area

95.86 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

588

Synonyms & References

English

  • (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-hydroxyphenyl)propanoic acid
  • FMOC-(R)-3-AMINO-3-(3-HYDROXY-PHENYL)-PROPIONIC ACID
  • Fmoc-(R)-3-Amino-3-(3-hydroxyphenyl)-propionic acid
  • Fmoc-D-β-Phe(3-OH)-OH
  • (3R)-3-[(FLUOREN-9-YLMETHOXY)CARBONYLAMINO]-3-(3-HYDROXYPHENYL)PROPANOIC ACID
  • AC1MC5P7
  • CTK4J3710
  • FMOC-PHG(3-OH)-(C*CH2)OH
  • MolPort-003-794-353
  • PubChem24053
  • Fmoc-(R)-3-Amino-3-(3-hydroxy-phenyl)-propionic acid
  • 511272-35-8
  • MFCD03428016
  • AC-25421
  • (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(3-hydroxyphenyl)propanoic Acid
  • AKOS015948874
  • Fmoc-R-3-Amino-3-(3-hydroxyphenyl)propionic acid
  • fmoc-(r)-3-amino-3-(3-hydroxyphenyl)propanoic acid
  • C15894
  • (3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(3-hydroxyphenyl)propanoic acid
  • Fmoc-(R)-3-Amino-3-(3-hydroxy-phenyl)propionic acid
  • PS-12491
  • DTXSID60375903

MDL Number

MFCD03428016

FAQ

What are the physical and chemical properties of (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-hydroxyphenyl)propanoic acid (CAS: 511272-35-8)?

The compound has a crystalline form, with a molecular weight of approximately 444.45 g/mol. It is sparingly soluble in water but soluble in organic solvents like methanol and ethanol. Chemically, it is relatively stable but can react with strong bases. It has a specific reactivity profile suitable for coupling reactions and esterification processes.

How is (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-hydroxyphenyl)propanoic acid (CAS: 511272-35-8) typically synthesized?

It is commonly synthesized via a multi-step process involving a fluorenylmethoxycarbonyl (Fmoc) protection, followed by coupling with a 3-hydroxybenzylamine derivative. The final step often involves deprotection and acidification. This synthesis typically yields a product with high purity and requires the use of fluorophiles and protecting groups.

What industries use (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-hydroxyphenyl)propanoic acid (CAS: 511272-35-8)?

This compound is primarily used in the pharmaceutical industry for the synthesis of complex organic molecules, including potential drug candidates. It is also applicable in polymer chemistry for the modification of polymer chains and in the development of new materials. Additionally, it can be used in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-hydroxyphenyl)propanoic acid (CAS: 511272-35-8)?

Proper personal protective equipment (PPE) should be worn when handling this compound, including gloves, goggles, and lab coats. It should be stored in a cool, dry place, away from strong acids and bases. In case of spillage, handle with care and refer to the Safety Data Sheet (SDS) for specific guidelines. Always use a fume hood to minimize inhalation risks.

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